Recurrent Henoch-Schönlein purpura in children

J Clin Rheumatol. 2007 Feb;13(1):25-8. doi: 10.1097/01.rhu.0000255692.46165.19.

Abstract

Background: Henoch-Schönlein purpura (HSP), also known as anaphylactoid purpura is a clinically recognizable systemic disorder occurring in children, mainly from ages 3 to 10 years.

Objectives: To describe the clinical, epidemiological, and laboratory findings in a group of patients with recurrent HSP, admitted to a tertiary pediatric center.

Methods: Retrospective analysis of medical records of patients hospitalized due to HSP between 1969 and 2004.

Results: Two hundred sixty children (56.7% males) were hospitalized due to HSP, 7 (2.7%) more than once. There were no statistically significant differences in demographic or clinical characteristics between the patients with 1 event of HSP and patients with recurrence. Mean age of the subgroup with recurrence was 3.67 years (10 months to 7.4 years) at the first episode, and 5.03 years (2.2-10 years) at the second one, with a mean lag period of 13.5 +/- 2.8 months (range 2-26). The duration of the recurrent clinical symptoms ranged from 9 to 30 days, and in 72% of those patients, resolution took more than 14 days.

Conclusion: In our inpatient population, no clinical or laboratory characteristics were found to be predictive of recurrence; the second episode was longer than the first and the lag period between the 2 episodes was substantially longer than previously reported. Hospital admissions for recurrent HSP are not common. Nevertheless, a good prognosis was the rule of our admitted patients.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Humans
  • IgA Vasculitis / complications*
  • IgA Vasculitis / epidemiology*
  • IgA Vasculitis / pathology
  • Incidence
  • Infant
  • Male
  • Patient Readmission
  • Recurrence
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Time Factors