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Prophecies of childhood: How children’s social environments and biological propensities affect the health of populations

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Abstract

During the past decade, important steps have been taken globally to improve the status of children. Concurrently, significant advances have been made toward understanding how child development is shaped by transactions between biological and environmental influences. Despite such advances, ongoing adversities in the lives of children worldwide undermine the development of individuals and thus the health of nations. The primary tenets of this paper are that: children continue to suffer a disproportionate share of the world’s adversities; exposure to early adversities is not only associated with increased morbidity during childhood, but also across the lifespan; and recent advances in understanding the operation and ontogeny of stress-response systems can help explain how adversity is translated into lifelong effects on health. Acknowledging the long-lasting sequelae of childhood adversity has important implications for public health and society.

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References

  • Alam, N., Saha, S. K., Razzaque, A., & van Ginneken, J. K. (2001). The effect of divorce on infant mortality in a remote area of Bangladesh. Journal of Biosocial Science, 33(2), 271–278.

    Article  PubMed  Google Scholar 

  • Ali, M. M., & Shah, I. H. (2000). Sanctions and childhood mortality in Iraq. Lancet, 355(9218), 1851–1857.

    Article  PubMed  Google Scholar 

  • Alkon, A., Goldstein, L. H., Smider, N., Essex, M. J., Kupfer, D. J., & Boyce, W. T. (2003). Developmental and contextual influences on autonomic reactivity in young children. Developmental Psychobiology, 42(1), 64–78.

    Article  PubMed  Google Scholar 

  • Ashman, S. B., Dawson, G., Panagiotides, H., Yamada, E., & Wilkins, C. W. (2002). Stress hormone levels of children of depressed mothers. Development and Psychopathology, 14(2), 333–349.

    Article  PubMed  Google Scholar 

  • Bar-Haim, Y., Marshall, P. J., & Fox, N. A. (2000). Developmental changes in heart period and high-frequency heart period variability from 4 months to 4 years of age. Developmental Psychobiology, 37(1), 44–56.

    Article  PubMed  Google Scholar 

  • Barker, D. J. (1997). The fetal origins of coronary heart disease. Acta Paediatrica. Supplement, 422, 78–82.

    PubMed  Google Scholar 

  • Barker, D. J. (2001). A new model for the origins of chronic disease. Medicine, Health Care and Philosophy, 4(1), 31–35.

    Article  Google Scholar 

  • Bauer, A. M., & Boyce, W. T. (2004). Concurrent sympathetic and adrenocortical activity as correlates of behavior in middle childhood. Unpublished manuscript.

  • Bhuiya, A., & Chowdhury, M. (1997). The effect of divorce on child survival in a rural area of Bangladesh. Population Studies, 51(1), 57–61.

    Article  PubMed  Google Scholar 

  • Boyce, W. T. (1996). Biobehavioral reactivity and injuries in children and adolescents. In M. Bornstein & J. Genevro (Eds.) Child development and behavioral pediatrics. (pp. 35–58). Mahwah, N J: Lawrence Erlbaum Associates, Inc., Publishers.

    Google Scholar 

  • Boyce, W. T., Chesney, M., Alkon, A., Tschann, J. M., Adams, S., Chesterman, B., et al. (1995). Psychobiologic reactivity to stress and childhood respiratory illnesses: Results of two prospective studies. Psychosomatic Medicine, 57(5), 411–422.

    PubMed  Google Scholar 

  • Boyce, W. T., & Ellis, B. J. (in press). Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity. Development and Psychopathology.

  • Boyce, W. T., Essex, M. J., Woodward, H. R., Measelle, J. R., Ablow, J. C., Kupfer, D. J., et al. (2002). The confluence of mental, physical, social, and academic difficulties in middle childhood: I. Exploring the “headwaters” of early life morbidities. Journal of the American Academy of Child & Adolescent Psychiatry, 41(5), 580–587.

    Article  Google Scholar 

  • Boyce, W. T., Quas, J., Alkon, A., Smider, N. A., Essex, M. J., Kupfer, D. J., et al. (2001). Autonomic reactivity and psychopathology in middle childhood. British Journal of Psychiatry, 179, 144–150.

    Article  PubMed  Google Scholar 

  • Brooks-Gunn, J., Duncan, G. J., & Britto, P. R. (1999). Are socioeconomic gradients for children similar to those for adults?: Achievement and health of children in the United States. In Developmental health and the wealth of nations: Social, biological, and educational dynamics. (pp. 94–124). New York, NY, US: The Guilford Press.

    Google Scholar 

  • Carlson, M., & Earls, F. (1997). Psychological and neuroendocrinological sequelae of early social deprivation in institutionalized children in Romania. Annals of the New York Academy of Sciences, 807, 419–428.

    Article  PubMed  Google Scholar 

  • Carrion, V. G., Weems, C. F., Ray, R. D., Glaser, B., Hessl, D., & Reiss, A. L. (2002). Diurnal salivary cortisol in pediatric posttraumatic stress disorder. Biological Psychiatry, 51(7), 575–582.

    Article  PubMed  Google Scholar 

  • Chen, E., Matthews, K. A., & Boyce, W. T. (2002). Socioeconomic differences in children’s health: How and why do these relationships change with age? Psychological Bulletin, 128(2), 295–329.

    Article  PubMed  Google Scholar 

  • Cicchetti, D., & Rogosch, F. A. (2001). Diverse patterns of neuroendocrine activity in maltreated children. Development and Psychopathology, 13(3), 677–693.

    Article  PubMed  Google Scholar 

  • Corry, D. B., & Tuck, M. L. (2001). Selective aspects of the insulin resistance syndrome. Current Opinion in Nephrology and Hypertension, 10(4), 507–514.

    Article  PubMed  Google Scholar 

  • Custovic, A., & Woodcock, A. (2001). Exposure and sensitization in infants and children. Current Opinion in Clinical Immunology, 1(2), 133–138.

    Google Scholar 

  • Daponte, B. O., & Garfield, R. (2000). The effect of economic sanctions on the mortality of Iraqi children prior to the 1991 Persian Gulf War. American Journal of Public Health, 90(4), 546–552.

    Article  PubMed  Google Scholar 

  • Dawson, G., Ashman, S. B., & Carver, L. J. (2000). The role of early experience in shaping behavioral and brain development and its implications for social policy. Development and Psychopathology, 12(4), 695–712.

    Article  PubMed  Google Scholar 

  • De Bellis, M. D., Baum, A. S., Birmaher, B., Keshavan, M. S., Eccard, C. H., Boring, A. M., et al. (1999). Developmental traumatology. Part I: Biological stress systems. Biological Psychiatry, 45(10), 1259–1270.

    Article  PubMed  Google Scholar 

  • De Bellis, M. D., Chrousos, G. P., Dorn, L. D., Burke, L., Helmers, K., Kling, M. A., et al. (1994). Hypothalamic-pituitary-adrenal axis dysregulation in sexually abused girls. Journal of Clinical Endocrinology and Metabolism, 78(2), 249–255.

    Article  PubMed  Google Scholar 

  • De Ronchi, D., Fratiglioni, L., Rucci, P., Paternico, A., Graziani, S., & Dalmonte, E. (1998). The effect ofeducation on dementia occurrence in an Italian population with middle to high socioeconomic status. Neurology, 50(5), 1231–1238.

    PubMed  Google Scholar 

  • Dennison, E., Hindmarsh, P., Fall, C., Kellingray, S., Barker, D., Phillips, D., et al. (1999). Profiles of endogenous circulating cortisol and bone mineral density in healthy elderly men. Journal of Clinical Endocrinology and Metabolism, 84(9), 3058–3063.

    Article  PubMed  Google Scholar 

  • Dobkin, P. L., Tremblay, R. E., & Treiber, F. A. (1998). Cardiovascular reactivity and adolescent boys’ physical health. Pediatrics, 101(3), E11.

    Article  PubMed  Google Scholar 

  • Dube, S. R., Anda, R. F., Felitti, V. J., Chapman, D. P., Williamson, D. F., & Giles, W. H. (2001). Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: Findings from the Adverse Childhood Experiences Study. Journal of the American Medical Association, 286(24), 3089–3096.

    Article  PubMed  Google Scholar 

  • Ellis, B. J., Essex, M. J., & Boyce, W. T. (in press). Biological sensitivity to context: II. Tests of an evolutionary-developmental hypothesis.

  • Epel, E., McEwen, B., Seeman, T., Matthews, K., Castellazzo, G., Brownell, K. D., et al. (2000). Stress and body shape: Stress-induced cortisol secretion is consistently greater among women with central fat. Psychosomatic Medicine, 62(5), 623–632.

    PubMed  Google Scholar 

  • Essex, M. J., Klein, M. H., Cho, E., & Kalin, N. H. (2002). Maternal stress beginning in infancy may sensitize children to later stress exposure: Effects on cortisol and behavior. Biological Psychiatry, 52(8), 776–784.

    Article  PubMed  Google Scholar 

  • Evans, D. A., Hebert, L. E., Beckett, L. A., Scherr, P. A., Albert, M. S., Chown, M. J., et al. (1997). Education and other measures of socioeconomic status and risk of incident Alzheimer disease in a defined population of older persons. Archives of Neurology, 54(11), 1399–1405.

    PubMed  Google Scholar 

  • Evans, G. W. (2003). A multimethodological analysis of cumulative risk and allostatic load among rural children. Developmental Psychology, 39(5), 924–933.

    Article  PubMed  Google Scholar 

  • Evans, G. W., & English, K. (2002). The environment of poverty: Multiple stressor exposure, psychophysiological stress, and socioemotional adjustment. Child Development, 73(4), 1238–1248.

    Article  PubMed  Google Scholar 

  • Fantuzzo, J. W., & Mohr, W. K. (1999). Prevalence and effects of child exposure to domestic violence. Future Child, 9(3), 21–32.

    Article  PubMed  Google Scholar 

  • Federal Interagency Forum on Child and Family Statistics. (2002). America’s children: Key national indicators of well-being 2002. Washington, D.C.: U.S. Government Printing Office.

    Google Scholar 

  • Felitti, V. (1991). Long-term medical consequences of incest, rape, and molestation. Southern Medical Journal, 84(3), 328–331.

    PubMed  Google Scholar 

  • Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., et al. (1998). Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: The Adverse Childhood Experiences (ACE) Study. American Journal of Preventive Medicine, 14(4), 245–258.

    Article  PubMed  Google Scholar 

  • Flinn, M. V., & England, B. G. (1995). Childhood stress and family environment. Current Anthropology, 36(5), 854–866.

    Article  Google Scholar 

  • Flinn, M. V., & England, B. G. (1997). Social economics of childhood glucocorticoid stress response and health. American Journal of Physical Anthropology, 102(1), 33–53.

    Article  PubMed  Google Scholar 

  • Goldstein, L. H., Trancik, A., Bensadoun, J., Boyce, W. T., & Adler, N. E. (1999). Social dominance and cardiovascular reactivity in preschoolers: Associations with SES and health. Annals of the New York Academy of Sciences, 896, 363–366.

    Article  PubMed  Google Scholar 

  • Gomby, D. S., Larner, M. B., Stevenson, C. S., Lewit, E. M., & Behrman, R. E. (1995). Long-term outcomes of early childhood programs: Analysis and recommendations. The Future of Children, 5(3), 6–24.

    Article  PubMed  Google Scholar 

  • Goodyer, I. M., Park, R. J., & Herbert, J. (2001). Psychosocial and endocrine features of chronic first-episode major depression in 8-16 year olds. Biological Psychiatry, 50(5), 351–357.

    Article  PubMed  Google Scholar 

  • Gunnar, M. R., & Donzella, B. (2002). Social regulation of the cortisol levels in early human development. Psychoneuroendocrinology, 27(1–2), 199–220.

    Article  PubMed  Google Scholar 

  • Gunnar, M. R., Morison, S. J., Chisholm, K., & Schuder, M. (2001). Salivary cortisol levels in children adopted from Romanian orphanages. Development and Psychopathology, 13(3), 611–628.

    Article  PubMed  Google Scholar 

  • Hall, K. S., Gao, S., Unverzagt, F. W., & Hendrie, H. C. (2000). Low education and childhood rural residence: Risk for Alzheimer’s disease in African Americans. Neurology, 54(1), 95–99.

    PubMed  Google Scholar 

  • Hart, J., Gunnar, M., & Cicchetti, D. (1995). Salivary cortisol in maltreated children: Evidence of relations between neuroendocrine activity and social competence. Development and Psychopathology, 7(1), 11–26.

    Google Scholar 

  • Hertsgaard, L., Gunnar, M., Erickson, M. F., & Nachmias, M. (1995). Adrenocortical responses to the strange situation in infants with disorganized/disoriented attachment relationships. Child Development, 66(4), 1100–1106.

    Article  PubMed  Google Scholar 

  • Hertzman, C. (1999a). The biological embedding of early experience and its effects on health in adulthood. Annals of the New York Academy of Sciences, 896, 85–95.

    Article  PubMed  Google Scholar 

  • Hertzman, C. (1999b). Population health and human development. In Developmental health and the wealth of nations: Social, biological, and educational dynamics. (pp. 21–40). New York: Guilford.

    Google Scholar 

  • Hertzman, C., & Wiens, M. (1996). Child development and long-term outcomes: A population health perspective and summary of successful interventions. Social Science & Medicine, 43(7), 1083–1095.

    Article  Google Scholar 

  • Huizenga, N. A., Koper, J. W., de Lange, P., Pols, H. A., Stolk, R. P., Grobbee, D. E., et al. (1998). Interperson variability but intraperson stability of baseline plasma cortisol concentrations, and its relation to feedback sensitivity of the hypothalamo-pituitary-adrenal axis to a low dose of dexamethasone in elderly individuals. Journal of Clinical Endocrinology and Metabolism, 83(1), 47–54.

    Article  PubMed  Google Scholar 

  • International Study Team. (2003). Our Common Responsibility: The Impact of a New War on Iraqi Children. Toronto: War Child Canada.

    Google Scholar 

  • Jensen, P. S., Richters, J., Ussery, T., Bloedau, L., & Davis, H. (1991). Child psychopathology and environmental influences: Discrete life events versus ongoing adversity. Journal of the American Academy of Child & Adolescent Psychiatry, 30(2), 303–309.

    Article  Google Scholar 

  • Kagan, J., Reznick, J. S., & Snidman, N. (1988). Biological bases of childhood shyness. Science, 240(4849), 167–171.

    Article  PubMed  Google Scholar 

  • Kataoka, S. H., Zhang, L., & Wells, K. B. (2002). Unmet need for mental health care among U.S. children: Variation by ethnicity and insurance status. American Journal of Psychiatry, 159(9), 1548–1555.

    Article  PubMed  Google Scholar 

  • Keating, D. P. (1999). Developmental health as the wealth of nations. In Developmental health and the wealth of nations: Social, biological, and educational dynamics. (pp. 337–347). New York: Guilford.

    Google Scholar 

  • Keating, D. P., & Hertzman, C. (1999). Developmental health and the wealth of nations: Social, biological, and educational dynamics. New York: Guilford.

    Google Scholar 

  • Klinnert, M. D., Nelson, H. S., Price, M. R., Adinoff, A. D., Leung, D. Y., & Mrazek, D. A. (2001). Onset and persistence of childhood asthma: Predictors from infancy. Pediatrics, 108(4), E69.

    Article  PubMed  Google Scholar 

  • Krug, E. G., Dahlberg, L. L., Mercy, J. A., Zwi, A. B., & Lozano, R. (2002). World report on violence and health. Geneva: World Health Organization.

    Google Scholar 

  • Kuh, D., & Ben-Shlomo, Y. (1997a). Introduction: A life course approach to the aetiology of adult chronic disease. In D. Kuh & Y. Ben-Shlomo (Eds.), A life course approach to chronic disease epidemiology: Tracing the origins of ill-health from early to adult life (pp. 3–14). New York: Oxford University Press.

    Google Scholar 

  • Kuh, D., & Ben-Shlomo, Y. (1997b). A life course approach to chronic disease epidemiology. Oxford; New York: Oxford University Press.

    Google Scholar 

  • Lachman, P., Poblete, X., Ebigbo, P. O., Nyandiya-Bundy, S., Bundy, R. P., Killian, B., et al. (2002). Challenges facing child protection. Child Abuse and Neglect, 26, 587–617.

    Article  PubMed  Google Scholar 

  • Lansford, J. E., Dodge, K. A., Pettit, G. S., Bates, J. E., Crozier, J., & Kaplow, J. (2002). A 12-year prospective study of the long-term effects of early child physical maltreatment on psychological, behavioral, and academic problems in adolescence. Archives of Pediatrics and Adolescent Medicine, 156(8), 824–830.

    PubMed  Google Scholar 

  • Lindsay, J., Laurin, D., Verreault, R., Hebert, R., Helliwell, B., Hill, G. B., et al. (2002). Risk factors for Alzheimer’s disease: a prospective analysis from the Canadian Study of Health and Aging. American Journal of Epidemiology, 156(5), 445–453.

    Article  PubMed  Google Scholar 

  • Luoma, I., Tamminen, T., Kaukonen, P., Laippala, P., Puura, K., Salmelin, R., et al. (2001). Longitudinal study of maternal depressive symptoms and child well-being. Journal of the American Academy of Child & Adolescent Psychiatry, 40(12), 1367–1374.

    Article  Google Scholar 

  • Lupien, S. J., King, S., Meaney, M. J., & McEwen, B. S. (2000). Child’s stress hormone levels correlate with mother’s socioeconomic status and depressive state. Biological Psychiatry, 48(10), 976–980.

    Article  PubMed  Google Scholar 

  • Luthar, S. S., & Cicchetti, D. (2000). The construct of resilience: Implications for interventions and social policies. Development and Psychopathology, 12(4), 857–885.

    Article  Google Scholar 

  • Machel, G., United Nations General Assembly, UNICEF, & United Nations Centre for Human Rights. (1996). Impact of armed conflict on children. New York: United Nations.

    Google Scholar 

  • Marshall, P. J., & Stevenson-Hinde, J. (1998). Behavioral inhibition, heart period, and respiratory sinus arrhythmia in young children. Developmental Psychobiology, 33(3), 283–292.

    Article  PubMed  Google Scholar 

  • Mason, J. W., Giller, E. L., Kosten, T. R., & Harkness, L. (1988). Elevation of urinary norepinephrine/cortisol ratio in posttraumatic stress disorder. Journal of Nervous and Mental Disease, 176(8), 498–502.

    Article  PubMed  Google Scholar 

  • Matthews, K. A. (1986). Handbook of stress, reactivity, and cardiovascular disease. New York: Wiley.

    Google Scholar 

  • Matthews, K. A., Woodall, K. L., & Stoney, C. M. (1990). Changes in and stability of cardiovascular responses to behavioral stress: results from a four-year longitudinal study of children. Child Development, 61(4), 1134–1144.

    Article  PubMed  Google Scholar 

  • McCauley, J., Kern, D. E., Kolodner, K., Dill, L., Schroeder, A. F., DeChant, H. K., et al. (1997). Clinical characteristics of women with ahistory of childhood abuse: Unhealed wounds. Journal of the American Medical Association, 277(17), 1362–1368.

    Article  PubMed  Google Scholar 

  • McEwen, B. S. (1998). Protective and damaging effects of stress mediators. New England Journal of Medicine, 338(3), 171–179.

    Article  PubMed  Google Scholar 

  • McEwen, B. S., & Stellar, E. (1993). Stress and the individual: Mechanisms leading to disease. Archives of Internal Medicine, 153(18), 2093–2101.

    Article  PubMed  Google Scholar 

  • Meaney, M. J. (2001). Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annual Review of Neuroscience, 24, 1161–1192.

    Article  PubMed  Google Scholar 

  • Meaney, M. J., Diorio, J., Francis, D., Widdowson, J., LaPlante, P., Caldji, C., et al. (1996). Early environmental regulation of forebrain glucocorticoid receptor gene expression: Implications for adrenocortical responses to stress. Developmental Neuroscience, 18(1–2), 49–72.

    Article  PubMed  Google Scholar 

  • Monk, C., Fifer, W. P., Myers, M. M., Sloan, R. P., Trien, L., & Hurtado, A. (2000). Maternal stress responses and anxiety during pregnancy: Effects on fetal heart rate. Developmental Psychobiology, 36(1), 67–77.

    Article  PubMed  Google Scholar 

  • Munck, A., Guyre, P. M., & Holbrook, N. J. (1984). Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocrine Reviews, 5(1), 25–44.

    PubMed  Google Scholar 

  • Nachmias, M., Gunnar, M., Mangelsdorf, S., Parritz, R. H., & Buss, K. (1996). Behavioral inhibition and stress reactivity: The moderating role of attachment security. Child Development, 67(2), 508–522.

    Article  PubMed  Google Scholar 

  • National Advisory Mental Health Council on Behavioral Science Workgroup. (2000). Translating behavioral science into action: Report of the National Advisory Mental Health Council on Behavioral Science Workgroup (NIH Publication No. 00-4699). Bethesda, MD: National Institutes of Health.

    Google Scholar 

  • O’Carroll, P. W., Potter, L. B., & Mercy, J. A. (1994). Programs for the prevention of suicide among adolescents and young adults. Morbidity and Mortality Weekly Report, 43(RR-6), 1–7.

    Google Scholar 

  • Pajer, K., Gardner, W., Rubin, R., Perel, J., & Neal, S. (2001). Decreased cortisol levels in adolescent girls with conduct disorder. Archives of General Psychiatry, 58, 297–302.

    Article  PubMed  Google Scholar 

  • Patel, V., DeSouza, N., & Rodrigues, M. (2003). Postnatal depression and infant growth and development in low income countries: A cohort study from Goa, India. Archives of Disease in Childhood, 88(1), 34–37.

    Article  PubMed  Google Scholar 

  • Platts-Mills, T., Vaughan, J., Squillace, S., Woodfolk, J., & Sporik, R. (2001). Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: A population-based cross-sectional study. Lancet, 357(9258), 752–756.

    Article  PubMed  Google Scholar 

  • Ponirakis, A., Susman, E. J., & Stifter, C. A. (1998). Negative emotionality and cortisol during adolescent pregnancy and its effects on infant health and autonomic nervous system reactivity. Developmental Psychobiology, 33(2), 163–174.

    Article  PubMed  Google Scholar 

  • Power, C., Manor, O., & Matthews, S. (1999). The duration and timing of exposure: Effects of socioeconomic environment on adult health. American Journal of Public Health, 89(7), 1059–1065.

    Article  PubMed  Google Scholar 

  • Raine, A., Venables, P. H., & Mednick, S. A. (1997). Low resting heart rate at age 3 years predisposes to aggression at age 11 years: Evidence from the Mauritius Child Health Project. Journal of the American Academy of Child & Adolescent Psychiatry, 36(10), 1457–1464.

    Article  Google Scholar 

  • Ravaglia, G., Forti, P., Maioli, F., Sacchetti, L., Mariani, E., Nativio, V., et al. (2002). Education, occupation, and prevalence of dementia: Findings from the conselice study. Dementia and Geriatric Cognitive Disorders, 14(2), 90–100.

    Article  PubMed  Google Scholar 

  • Regier, D. A., Narrow, W. E., Rae, D. S., & Manderscheid, R. W. (1993). The de facto US mental and addictive disorders service system: Epidemiologic Catchment Area prospective 1-year prevalence rates of disorders and services. Archives of General Psychiatry, 50(2), 85–94.

    PubMed  Google Scholar 

  • Repetti, R. L., Taylor, S. E., & Seeman, T. E. (2002). Risky families: Family social environments and the mental and physical health of offspring. Psychological Bulletin, 128(2), 330–366.

    Article  PubMed  Google Scholar 

  • Roseboom, T. J., van der Meulen, J. H., Ravelli, A. C., Osmond, C., Barker, D. J., & Bleker, O. P. (2001). Effects of prenatal exposure to the Dutch famine on adult disease in later life: An overview. Molecular and Cellular Endocrinology, 185(1–2), 93–98.

    Article  PubMed  Google Scholar 

  • Salomon, K., Matthews, K. A., & Allen, M. (2000). Patterns of sympathetic and parasympathetic reactivity in a sample of children and adolescents. Psychophysiology, 37(6), 842–849.

    Article  PubMed  Google Scholar 

  • Sapolsky, R. M. (2000). Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Archives of General Psychiatry, 57(10), 925–935.

    Article  PubMed  Google Scholar 

  • Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000). How do glucocorticoids influence stress responses?: Integrating permissive, suppressive, stimulatory, and preparative actions. Endocrine Reviews, 21(1), 55–89.

    Article  PubMed  Google Scholar 

  • Schwartz, J. E., Friedman, H. S., Tucker, J. S., Tomlinson-Keasey, C., Wingard, D. L., & Criqui, M. H. (1995). Sociodemographic and psychosocial factors in childhood as predictors of adult mortality. American Journal of Public Health, 85(9), 1237–1245.

    Article  PubMed  Google Scholar 

  • Shonkoff, J. P., Phillips, D., Board on Children Youth and Families, & Committee on Integrating the Science of Early Childhood Development (Eds.). (2000). From neurons to neighborhoods: The science of early childhood development. Washington, D.C.: National Academy Press.

    Google Scholar 

  • Smith, P., Perrin, S., Yule, W., & Rabe-Hesketh, S. (2001). War exposure and maternal reactions in the psychological adjustment of children from Bosnia-Hercegovina. Journal of Child Psychology and Psychiatry and Allied Disciplines, 42(3), 395–404.

    Article  Google Scholar 

  • Sterling, P., & Eyer, J. (1988). Allostasis: A new paradigm to explain arousal pathology. In S. Fisher & J. Reason (Eds.), Handbook of life stress, cognition and health. (pp. 629–649). New York: Wiley.

    Google Scholar 

  • Stern, Y., Albert, S., Tang, M. X., & Tsai, W. Y. (1999). Rate of memory decline in AD is related to education and occupation: Cognitive reserve? Neurology, 53(9), 1942–1947.

    PubMed  Google Scholar 

  • Stern, Y., Gurland, B., Tatemichi, T. K., Tang, M. X., Wilder, D., & Mayeux, R. (1994). Influence of education and occupation on the incidence of Alzheimer’s disease. Journal of the American Medical Association, 271(13), 1004–1010.

    Article  PubMed  Google Scholar 

  • Suomi, S. J. (1999). Developmental trajectories, early experiences, and community consequences: Lessons from studies with rhesus monkeys. In Developmental health and the wealth of nations: Social, biological, and educational dynamics. (pp. 185–200). New York: Guilford.

    Google Scholar 

  • Talley, N. J., Fett, S. L., Zinsmeister, A. R., & Melton, L. J. R. (1994). Gastrointestinal tract symptoms and self-reported abuse: A population-based study. Gastroenterology, 107(4), 1040–1049.

    PubMed  Google Scholar 

  • Tyas, S. L., Manfreda, J., Strain, L. A., & Montgomery, P. R. (2001). Risk factors for Alzheimer’s disease: A population-based, longitudinal study in Manitoba, Canada. International Journal of Epidemiology, 30(3), 590–597.

    Article  PubMed  Google Scholar 

  • UNAIDS. (2002). Report on the global HIV/AIDS epidemic 2002. New York: Joint United Nations Programme on HIV/AIDS.

    Google Scholar 

  • UNICEF. (1999). Children orphaned by AIDS: Front-line responses from eastern and southern Africa. New York: UNICEF.

    Google Scholar 

  • UNICEF. (2000a). Poverty reduction begins with children. New York: UNICEF.

    Google Scholar 

  • UNICEF. (2000b). The state of the world’s children. New York: UNICEF.

    Google Scholar 

  • UNICEF. (2002a). The state of the world’s children. New York: UNICEF.

    Google Scholar 

  • UNICEF. (2002b). The state of the world’s children —summary. New York: UNICEF.

    Google Scholar 

  • United Nations. (1998). Too young to die: Genes or gender? New York: United Nations Department of Economic and Social Affairs Population Division.

    Google Scholar 

  • van Goozen, S. H. M., Matthys, W., Cohen-Kettenis, P. T., Buitelaar, J. K., & van Engeland, H. (2000). Hypothalamic-pituitary-adrenal axis and autonomic nervous system activity in disruptive children and matched controls. Journal of the American Academy of Child & Adolescent Psychiatry, 39(11), 1438–1445.

    Article  Google Scholar 

  • van Goozen, S. H. M., Matthys, W., Cohen-Kettenis, P. T., Gispen-de Wied, C., Wiegant, V. M., & van Engeland, H. (1998). Salivary cortisol and cardiovascular activity during stress in oppositional-defiant disorder boys and normal controls. Biological Psychiatry, 43(7), 531–539.

    Article  PubMed  Google Scholar 

  • Vicennati, V., & Pasquali, R. (2000). Abnormalities of the hypothalamic-pituitary-adrenal axis in nondepressed women with abdominal obesity and relations with insulin resistance: Evidence for a central and a peripheral alteration. Journal of Clinical Endocrinology and Metabolism, 85(11), 4093–4098.

    Article  PubMed  Google Scholar 

  • Wadhwa, P., Glynn, L., Hobel, C., Garite, T., Porto, M., Chicz-DeMet, A., et al. (2002). Behavioral perinatology: Biobehavioral processes in human fetal development. Regulatory Peptides, 108(2–3), 149–157.

    Article  PubMed  Google Scholar 

  • Walker, E. A., Gelfand, A. N., Gelfand, M. D., & Katon, W. J. (1995). Psychiatric diagnoses, sexual and physical victimization, and disability in patients with irritable bowel syndrome or inflammatory bowel disease. Psychological Medicine, 25(6), 1259–1267.

    Article  PubMed  Google Scholar 

  • Walker, E. F., Walder, D. J., & Reynolds, F. (2001). Developmental changes in cortisol secretion in normal and at-risk youth. Development and Psychopathology, 13(3), 721–732.

    Article  PubMed  Google Scholar 

  • WHO International Consortium in Psychiatric Epidemiology. (2000). Cross-national comparisons of the prevalences and correlates of mental disorders. Bulletin of the World Health Organization, 78(4), 413–426.

    Google Scholar 

  • Willemsen-Swinkels, S. H., Bakermans-Kranenburg, M. J., Buitelaar, J. K., van Ijzendoorn, M. H., & van Engeland, H. (2000). Insecure and disorganised attachment in children with a pervasive developmental disorder: Relationship with social interaction and heart rate. Journal of Child Psychology and Psychiatry, 41(6), 759–767.

    Article  PubMed  Google Scholar 

  • Wolf, A. W., De Andraca, I., & Lozoff, B. (2002). Maternal depression in three Latin American samples. Social Psychiatry and Psychiatric Epidemiology, 37(4), 169–176.

    Article  PubMed  Google Scholar 

  • World Health Organization. (2003). Diet, nutrition, and the prevention of chronic diseases: Report of a WHO study group. Geneva: Author.

    Google Scholar 

  • Yehuda, R. (2001). Biology of posttraumatic stress disorder. Journal of Clinical Psychiatry, 62(Suppl.), 41–46.

    PubMed  Google Scholar 

  • Yehuda, R., Resnick, H.S., Schmeidler, J., Yang, R.-K., & Pitman, R. K. (1998). Predictors of cortisol and 3-Methoxy-4- hydroxy-phenylglycol responses in the acute aftermath of rape. Biological Psychiatry, 43(11), 855–859.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Psychiatry, Massachusetts General Hospital and McLean Hospital, Bulfinch 440, 02114, Boston, Massachusetts, USA

    Amy M. Bauer

  2. Institute of Human Development and School of Public Health, University of California, Berkeley, California, USA

    W. Thomas Boyce

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  1. Amy M. Bauer
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  2. W. Thomas Boyce
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Correspondence to Amy M. Bauer.

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Bauer, A.M., Boyce, W.T. Prophecies of childhood: How children’s social environments and biological propensities affect the health of populations. Int. J. Behav. Med. 11, 164–175 (2004). https://doi.org/10.1207/s15327558ijbm1103_5

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