Journal of the American Academy of Child & Adolescent Psychiatry
ARTICLESCase Series: Increased Vulnerability to Obsessive-Compulsive Symptoms With Repeated Episodes of Sydenham Chorea
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Post-infectious autoimmune disorders: Sydenham's chorea, PANDAS and beyond
2015, Brain ResearchCitation Excerpt :Multiple psychiatric comorbidities have been reported (Moreira et al., 2014; Ridel et al., 2010), with emotional labiality and anxiety disorders showing the highest prevalence (Taranta and Stollerman, 1956; Ridel et al., 2010). Of the investigations which specify the nature of anxiety symptoms associated with SC, the most consistently reported are symptoms of obsessive compulsive disorder (OCD) (Moreira et al., 2014; Asbahr et al., 2005a, 2005b, 1999, 1998; Swedo et al., 1993, 1989; Mercadante et al., 2005; Hounie et al., 2004). The categories of OCD symptoms (e.g., contamination fears, aggressive thoughts) in children with SC are consistent with those of childhood onset OCD (Asbahr et al., 2005), and are appear abruptly in the weeks preceding the onset of chorea in SC (Asbahr et al., 2005; Swedo, 1994).
Acute and Chronic Chorea in Childhood
2009, Seminars in Pediatric NeurologyCitation Excerpt :Symptom severity varies widely but generally there is difficulty with fine motor tasks. Parents often report personality changes, including inattention, anxiety, obsessive compulsiveness, paranoia, and reluctance to speak.18-22 Interestingly, children with rheumatic fever not only commonly develop obsessive compulsive symptoms, they also have a higher than expected prevalence of these symptoms in first-degree relatives.23
Antibody-mediated neuronal cell signaling in behavior and movement disorders
2006, Journal of NeuroimmunologyPediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)
2004, Infection and Autoimmunity, 2nd editionSydenham's chorea: Not gone and not forgotten
2003, Seminars in Pediatric NeurologyNeuropsychology of obsessive-compulsive disorder: A review and treatment implications
2003, Clinical Psychology Review
This work was supported by Fundação de Amparo à Pesquisa do Estado de São Paulo: grants 96/09046–6 and 98/15247–0 to Dr. Asbahr and grant 95/0194–0 to Dr. Gentil.