Liver transplantationOutcomeLiving Related Donor Liver Transplantation in Children
Section snippets
Methods
We performed a chart analysis of 121 LRDLT performed at our institution between June 1998 and June 2010. All patients were identified by retrospective review of a prospectively acquired liver database that contained recipient and donor demographics, perioperative findings, and postoperative outcomes.
Donors
The donors included 71 mothers, 45 fathers, 2 uncles, 1 grandmother, 1 grandfather, and 1 sister with a median age of 29 years (range, 16–53) and a median weight of 68 kg (range, 47–106).
The liver grafts consisted of the left lateral segment with the left hepatic vein in 108 cases or an extended left lateral segment, which always included the left and middle hepatic veins, in 12 donors. One case used the right hepatic lobe. The median duration of the donor surgeries was 6.8 hours (range, 4.3–11
Discussion
LRDLT has become a good option to provide suitable grafts for children with liver diseases, mainly in developing countries, where cadaveric donation systems are still limited.2 Even in the pediatric/model of end-stage liver disease (PELD/MELD) era, when children and more severely ill patients are favored, LRDLT maintains its indisputable role. LRDLT is sometimes the only option available to save children with end-stage hepatic diseases, liver tumors, or fulminant hepatic failure.3
Because most
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Antithrombin supplementation for prevention of vascular thrombosis after pediatric liver transplantation
2022, Journal of Pediatric SurgeryCitation Excerpt :Interestingly, in the rare reported pediatric series using postoperative AT replacement therapy or FFP combined with low-molecular-weight heparin (LMWH), HAT rates are low between 0 and 1.8% [18–21]. In contrast, in large pediatric LT series using heparin therapy after LT without supplementation of anti thrombotic coagulation factors, HAT affects 3.4–11% of patients [4,22–24]. Current knowledge on the hemostatic balance after LT is mainly based on studies performed in adults and data in the pediatric population is scarce.
Pediatric Liver Transplantation in South America: Incidence and Indications
2020, Pediatric Liver TransplantationMetabolic Conditions
2020, Pediatric Liver TransplantationComparison of the Results of Living Donor Liver Transplantation Due to Acute Liver Failure and Biliary Atresia in a Quaternary Center
2017, Transplantation ProceedingsCitation Excerpt :Besides, the higher prevalence of gender disparity between donor and recipients in the ALF group may contribute also. Pediatric patients were the first liver recipients of living donors for two reasons: first, their relatives are potential donors with few ethical problems, and second, the donor's safety can be more easily preserved, leaving the right lobe intact after the withdrawal of the left lobe [16]. In the present study, the donors presented no severe complications or deaths in any of the groups.
Liver transplantation using grafts with rare metabolic disorders
2015, Digestive and Liver Disease