Liver transplantationExperience of Living Donor Liver Transplantation in Iran: A Single-Center Report
Section snippets
Patients and Methods
Between January 1997 and March 2008, 50 patients with end-stage liver diseases received partial liver grafts from living donors. All surgical procedures were performed by same transplant surgeons. The demographics of the living donors and the recipients are listed in Table 1.
Results
Among 50 patients, 30 were males and 20 females. The mean age of the patients was 7.21 ± 5.34 years old at the time of operation. The most common indications for LDLT were end-stage liver disease due to Wilson's disease (16%); cryptogenic cirrhosis (16%); tyrosinemia (14%); biliary atresia (12%); autoimmune hepatitis (12%); and progressive familial intrahepatic cholestasis (12%). At the onset of the symptoms 18 patients were less than 2 years old; 13, between 2 and 5 years; and 19 more than 5
Discussion
In recent years, surgical techniques have improved and new immunosuppressive agents have been introduced, but the number of potential donor organs is far out of proportion to the increasing demand for liver transplantation. Deceased donor liver transplantation has rescued many patients with end-stage liver diseases, but its availability is limited. LDLT may be a useful alternative to overcome the organ shortage and reduce list mortality. The donor hepatectomy, especially a right lobe
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