Registry reportRegistry of the International Society for Heart and Lung Transplantation: Tenth Official Pediatric Heart Transplantation Report—2007
Section snippets
Statistical Methods
Survival rates were calculated using the Kaplan–Meier method and were compared using the log-rank test described previously.2 Multivariate analyses were performed using proportional hazards regression models. The impact of continuous risk factors was examined with restricted cubic splines. Predicted survival curves were again generated for specific hypothetical patient/donor/transplant profiles, as reported previously.1
Volumes and Indications
The total number of pediatric heart transplant procedures reported to the Registry of the ISHLT has remained reasonably stable for the past 15 years at approximately 400 procedures per year (Figure 1). As reported previously, the first year of life is the single most common year for a heart transplant procedure during the first 18 years of life. The total number of donors is also greatest in the early childhood years.
The total number of transplant centers reporting data has stabilized at
Conclusions
This Tenth Official Pediatric Registry Report of the ISHLT honors 25 years of pediatric heart transplantation and all the international centers and individuals involved. The data on late survival are impressive and unique to pediatrics. The lower risk of graft vasculopathy compared with adult recipients and the decreased risk of late death in infant recipients may provide insights into biologic mechanisms. Challenges remain including for those who may require re-transplantation. The newer tools
References (3)
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The registry of the International Society for Heart and Lung Transplantation: fifth official pediatric report—2001 to 2002
J Heart Lung Transplant
(2002)
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All of the figures and tables from this report and a more comprehensive set of Registry slides are available at http://www.ishlt.org/registries/.