Elsevier

Public Health

Volume 110, Issue 2, March 1996, Pages 85-94
Public Health

Lifecourse exposure and later disease: a follow-up study based on a survey of family diet and health in pre-war Britain (1937–1939)

https://doi.org/10.1016/S0033-3506(96)80052-7Get rights and content

Abstract

There is an increasing interest in the origins of adult disease in early life. The elucidation of such explanations of current morbidity and mortality must depend upon the follow-up of previously established cohorts. This paper describes the design of and background to such a follow-up of one of the richest data sources for this type of research: Sir John Boyd Orr's survey of diet and health in pre-war Britain. 1,352 families from 16 centres in England and Scotland were surveyed; 3,762 children aged up to 19 years from these families were examined. Socio-economic information and detailed one week dietary diary records are available for all families. Detailed medical examinations (including anthropometry) were undertaken on children in 14 of the centres. Most of the information is cross-sectional although 1,322 children were examined on two or more occasions one year apart to assess the effects of dietary supplementation. Dietary records were retrieved for 1,343 (99.3%) of the families. Medical examination records were found for 3,560 (94.6%) of the children who were examined in the survey and attempts have been made to trace 4,973 children who were either examined or whose family participated in the dietary survey. The data demonstrate relationships between family food expenditure and height in childhood and housing conditions. Eighty-five per cent (4211/4973) of the children have been traced and flagged on the National Health Service Central Register, Southport. The characteristics of those traced do not differ significantly from those we have been unable to trace although untraced females were slightly heavier. To date 696 (16.5%) of the cohort have died. The cohord will be used to investigate the relationship between diet, nutritional status (height, weight, cristal height), health and social circumstances in childhood, and mortality and morbidity in adulthood.

References (55)

  • BarkerDJP et al.

    The maternal and fetal origins of cardiovascular disease

    J Epidemiol Community Health

    (1992)
  • BarkerDJP

    Fetal and infant origins of adult disease

    (1992)
  • ForsdahlA

    Living conditions in childhood and subsequent development of risk factors for arteriosclerotic heart disease. The cardiovascular survey in Finnmark1974–1975

    J Epidemiol Community Health

    (1978)
  • WilliamsDRR et al.

    Deaths from ischaemic heart disease and infant mortality in England and Wales

    J Epidemiol Community Health

    (1979)
  • BuckC et al.

    Infant diarrhoea and subsequent mortality from heart disease and cancer

    J Epidemiol Comunity Health

    (1982)
  • BarkerDJP et al.

    Death rates from stroke in England and Wales predicted from past maternal mortality

    BMJ

    (1987)
  • BarkerDJP et al.

    The intrauterine and early postnatal origins of cardiovascular disease and chronic brochitis

    J Epidemiol Community Health

    (1989)
  • BarkerDJP et al.

    Height and mortality in the counties of England and Wales

    Ann Hum Biol

    (1990)
  • BarkerDJP et al.

    Relation of birth weight and childhood respiratory infection to adult lung function and death from chronic obstructive airways disease

    BMJ

    (1991)
  • BarkerDJP et al.

    Fetal and placental size and risk of hypertensien in adult life

    BMJ

    (1990)
  • ArnesenE et al.

    The Tromso heart study: coronary risk factors and their association with living conditions during childhood

    J Epidemiol Community Health

    (1985)
  • KaplanGA et al.

    The decline in Ischemic Heart Disease Mortality: Prospective evidence from the Alameda County Study

    Am J Epidemiol

    (1988)
  • NietoFJ et al.

    Childhood weight and growth rate as predictors of adult mortality

    Am J Epidemiol

    (1992)
  • TannerJM

    Foetus into Man

  • LaunerLJ et al.

    Relation between birth weight and blood pressure: longitudinal study of infants and children

    BMJ

    (1993)
  • HislopTG et al.

    Childhood and recent eating patterns and risk of breast cancer

    Cancer Detect Prev

    (1986)
  • SlatteryML et al.

    Food-consumption trends between adolescent and adult years and subsequent risk of prostate cancer

    Am J Clin Nutr

    (1990)
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