Atopic dermatitis and food hypersensitivity reactions☆,☆☆,★
Section snippets
Patients
Patients who met the criteria13 for the diagnosis of AD were enrolled in the study. The dermatitis ranged from mild to severe. The patients were from the Pediatric Allergy Clinic at Arkansas Children's Hospital; approximately 50% of patients receive their medical care entirely at the hospital (inner-city population), and 50% are referred (for their AD or other allergic diseases) from primary care physicians in Little Rock and central Arkansas. Parents were informed about the study on their
Entire Group (Group 1)
One hundred sixty-five patients (91 males) were enrolled and completed the study from 1986 through 1995. Patients ranged in age from 4 months to 21.9 years (mean age 48.9 months). The mean age of onset of dermatitis was 16 months (range birth to 20.5 years). The family history was positive for atopic disorders (allergic rhinitis, asthma, or AD) in 92% of the patients. Forty-nine (30%) children had asthma, 84 (51%) had allergic rhinitis, and 37 (22%) had both allergic rhinitis and asthma. Before
Discussion
Despite recent evidence supporting the clinical significance of food allergy in children with AD, this issue continues to be debated. In the studies by Sampson,15 > 60% of children with moderate to severe AD had positive food challenges. The interpretation of these studies for the primary care practitioner, however, has been difficult because of the severity of the AD. Overall, ~75% of these patients had used systemic steroids on at least one occasion before entering their study. In our
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Cited by (291)
Food allergy testing in atopic dermatitis
2022, JAAD InternationalPrevalence of food allergy diagnosis in pediatric patients with atopic dermatitis referred to allergy and/or dermatology subspecialty clinics
2022, Journal of Allergy and Clinical Immunology: In PracticeIgE testing can predict food allergy status in patients with moderate to severe atopic dermatitis
2019, Annals of Allergy, Asthma and ImmunologyAn approach to allergy risk assessments for e-liquid ingredients
2017, Regulatory Toxicology and PharmacologySensitization patterns among patients with atopic dermatitis evaluated in a large tertiary care pediatric center
2017, Annals of Allergy, Asthma and ImmunologyAssociation of food allergy and atopic dermatitis exacerbations
2016, Annals of Allergy, Asthma and Immunology
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From the Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children's Hospital Research Institute, Little Rock, Arkansas
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Reprint requests: Wesley Burks, MD, Pediatric Allergy and Immunology, Arkansas Children's Hospital, 800 Marshall Street, Little Rock, AR 72202.
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