Clinical and laboratory observationInduced sputum to diagnose Pneumocystis carinii pneumonia in immunosuppressed pediatric patients
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Cited by (43)
Induced sputum as an adequate clinical specimen for the etiological diagnosis of community-acquired pneumonia (CAP) in children and adolescents
2022, International Journal of Infectious DiseasesCitation Excerpt :Although obtaining spontaneous sputum samples in younger children is difficult and they often swallow the respiratory secretions, it is possible to induce an adequate sputum sample with a procedure that results in the movement of secretions from the lower respiratory tract and that induces effective cough using nebulization with hypertonic saline solution (Grant et al., 2012). This procedure has been described in microbiological studies of tuberculosis (TB), cystic fibrosis, Pneumocystis jirovecii pneumonia, and Cryptosporidium spp. infections and to assess airway inflammatory response in asthma (D'Sylva et al., 2017; Licari et al., 2020; Nyangulu et al., 2021; Ognibene et al., 1989). Therefore, IS represents an adequate and feasible diagnostic tool for obtaining lower respiratory tract samples to determine etiological agents, thus allowing for an accurate and prompt diagnosis of CAP in children and adolescents.
66 - Respiratory Disorders in Human Immunodeficiency Virus-Infected Children and Adolescents
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