Elsevier

The Journal of Pediatrics

Volume 109, Issue 5, November 1986, Pages 759-763
The Journal of Pediatrics

Original article
Clinical spectrum of Kawasaki disease in infants younger than 6 months of age1

https://doi.org/10.1016/S0022-3476(86)80689-8Get rights and content

We report an unselected series of eight patients younger than 6 months of age with Kawasaki disease evaluated between January 1982 and May 1984. The incidence of coronary artery aneurysms (six patients) and the mortality (two patients) were unusually high in this small series. Because of the confusing clinical presentation in three patients, diagnosis was delayed until pathologic or echocardiographic evidence of coronary vasculitis or aneurysm was discovered. The currently accepted clinical criteria for Kawasaki disease may not always identify patients with the pathologic findings of the syndrome who are younger than 6 months of age. The diagnosis of Kawasaki disease and echocardiographic evaluation of the coronary arteries should be considered in young infants with prolonged fever of unknown origin.

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Supported in part by Grant RR-69 from the General Clinical Research Centers Program of the Division of Research Resources, National Institutes of Health.

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