Brief clinical and laboratory observation
Carbamazepine-induced acute tubulointerstitial nephritis1

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    Hepatitis involvement is frequently asymptomatic (cytolytic hepatitis or cholestasis) but jaundice, hepatic failure, and fulminant hepatitis may occur. Other systemic involvements include nephritis, pancreatitis, pneumonitis, colitis, myocarditis, myositis, meningoencephalitis, parodititis, orchitis, and thyroiditis (Hogg et al., 1981; Engel et al., 1986; Gupta et al., 1992; Knowles et al., 1999; Sekine et al., 2001; Fujino et al., 2002). Clinical hematological involvement is observed in lymphadenopathy and hepatosplenomegaly.

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1

Presented in part at The American Society of Neprology 12th Annual, Meeting, November 20, 1979.

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