Deficient neurogenic innervation of the myenteric plexus with normal submucous plexus involving the entire small and large bowel*
References (11)
- et al.
Hypoganglionosis of the myenteric plexus with normal Meissner's plexus: A new variant of colonic ganglion cell disorders
J Pediatr Surg
(1985) - et al.
Absence of the enteric nervous system in the newborn: Presentation of three patients and review of the literature
J Pediatr Surg
(1986) - et al.
Total intestinal aganglionosis: A new technique for prolonged survival
J Pediatr Surg
(1987) - et al.
Hirschsprung's disease
Lancet
(1951) - et al.
Neuronal colonic dysplasia
J Pediatr Surg
(1977)
Cited by (9)
Counting myenteric ganglion cells in histologic sections: An empirical approach
2010, Human PathologyCitation Excerpt :Certainly, some severe forms of congenital or acquired (eg, Chagas disease, autoimmune enteric neuropathy) hypoganglionosis are well established and can be recognized without formal ganglion cell counts. However, milder forms of hypo- or hyperganglionosis have been postulated as the basis for other types of intestinal pseudo-obstruction or chronic constipation, often based on histologic impressions without either formal quantitative data or reliable controls [32-38]. Assessment of myenteric neuron density is particularly challenging for the general surgical pathologist, who has to rely on published criteria for neuronal identification and normative data, most of which are collected in a research context and have not been validated by other laboratories.
Embryologic and anatomic basis of duodenal surgery
2000, Surgical Clinics of North AmericaCitation Excerpt :Megaduodenum is most likely secondary to neuromotor function at the myenteric plexus of Auerbach, which produces a functional obstruction similar to that of patients with congenital megacolon. Mishalany et al40 reported on a case of a newborn infant with intestinal obstruction secondary to severe depletion of ganglion cells and nerve fibers at Auerbach's plexus; the submucous plexus of Meissner was normal. False diverticula of the duodenum (Fig. 5) are usually found on the concave wall of the second and third parts of the duodenum, often close to the duodenal papillae.
Advances in understanding functional variations in the Hirschsprung disease spectrum (variant Hirschsprung disease)
2017, Pediatric Surgery InternationalDifferences in the development of autogenous nerves between the upper and lower urinary tract
2013, Experimental and Therapeutic Medicine
- *
Presented at the 19th Annual Meeting of the American Pediatric Surgical Association, Tucson, Arizona, May 11–14, 1988.
- 1
From the Department of Surgery, Pathology, and Pediatrics, White Memorial Medical Center, Los Angeles; and the Division of Pediatric Surgery and Department of Pathology, Childrens Hospital of Los Angeles, University of Southern California, School of Medicine, Los Angeles.