Elsevier

The Lancet

Volume 335, Issue 8680, 6 January 1990, Pages 8-11
The Lancet

MEDICAL SCIENCE
Focal cerebral dysfunction in developmental learning disabilities

https://doi.org/10.1016/0140-6736(90)90136-SGet rights and content

Abstract

In 24 children with developmental learning disabilities and 15 age-matched controls regional cerebral activity was studied with xenon-133 single photon emission tomography. In the 9 children with pure attention deficit and hyperactivity disorder (ADHD), the distribution of regional cerebral activity was abnormal—low in striatal and posterior periventricular regions and high in occipital regions. Low activity in striatal and posterior periventricular areas was also seen in the 8 children with ADHD in combination with phonologic-syntactic dysphasia. 7 children with dysphasia, but without hyperactive behaviour, had low cerebral activity in left temporofrontal regions.

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