Review articleExercise-induced asthma
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Cited by (204)
Repurposing drugs as inhaled therapies in asthma
2018, Advanced Drug Delivery ReviewsParadoxic vocal fold movement disorder
2014, Otolaryngologic Clinics of North AmericaCitation Excerpt :Dyspnea tends to come on more quickly with PVFMD than with asthma. It also tends to resolve more quickly with rest, rather than becoming most severe after cessation of activity, as in exercise-induced bronchoconstriction.38,39 In elite athletes particularly, the dyspnea may be provoked only by high-intensity exercise rather than with long, lower-intensity workouts.
Approach to the Patient with Exercise-Induced Bronchoconstriction
2014, Middleton's Allergy: Principles and Practice: Eighth EditionRefractoriness to Exercise Challenge. A Review of the Mechanisms Old and New.
2013, Immunology and Allergy Clinics of North AmericaCitation Excerpt :“Exercise-induced bronchoconstriction (EIB) and exercise induced asthma are the terms used to describe the transient increase in airways resistance that follows vigorous exercise.”1 Most untreated patients with asthma will experience bronchoconstriction after exercise,2–4 and the prevalence of positive responses in those being treated with inhaled corticosteroids is about 50%.5,6 EIB is identified by measuring a decrease in forced expiratory volume in the first second of expiration (FEV1) after exercise of at least 10% to 15% from the pre-exercise value.
Exercise-Induced Bronchoconstriction. Celebrating 50 Years
2013, Immunology and Allergy Clinics of North AmericaCitation Excerpt :When tests were repeated at 2-hour intervals throughout the day, no significant diminution in EIB was found so that there was no refractoriness if the interval between challenges was 2 hours. In 1975 Anderson and colleagues37 summarized what was known about EIB up to that time but were forced to admit that the mechanisms involved in the production of EIB remained largely unknown. Even something as apparently obvious as the site of action of a β-agonist in preventing EIB received a jolt when Anderson and colleagues38 found that while an oral β-agonist, terbutaline, and an inhaled β-agonist, fenoterol, were equally effective as bronchodilators before and during exercise, only the inhaled drug prevented a post-exercise fall in lung function.
Assessment of Exercise-Induced Bronchoconstriction in Adolescents and Young Children
2013, Immunology and Allergy Clinics of North AmericaCitation Excerpt :EIB is characterized as a reduction in postexercise pulmonary function.3,12 The course of EIB in children generally consists of an initial bronchodilation early during exercise.12 The bronchoconstriction typically begins after cessation of exercise,4,13 but may start during exercise (“breakthrough” EIB),14,15 and peaks 2 to 15 minutes after exercise (Fig. 1),2,13,15,16 followed by spontaneous recovery of pulmonary function, which can last about 30 to 60 minutes.2,13
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Respiratory Physiology Unit, Page Chest Pavilion, Royal Prince Albert Hospital, Camperdown, New South Wales, 2050, Australia.
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Department of Paediatrics, Ahmadu Bello University, Zaria, Nigeria.
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Department of Paediatrics, Hammersmith Hospital, London W12 oHS UK.