Abstract
The aetiology of nephrolithiasis was investigated in 32 north Indian children (25 boys, 7 girls, mean age 7.9±3.3 years). An underlying disorder was detected in 16 (50%) patients and included idiopathic hypercalciuria (8 patients), hyperoxaluria (3 patients) and renal tubular acidosis, primary hyperparathyroidism and hyperuricosuria (1 patient each). Magnesium ammonium phosphate calculi were found in 2 patients with recurrent urinary tract infections, 1 of whom had a duplex pelvic collecting system. In 16 patients (50%) a cause for renal calculi was not identified. Our findings suggest that an underlying disorder is present in a large proportion of children with nephrolithiasis where appropriate treatment may be beneficial.
References
Aurora AL, Taneja OP, Gupta DN (1970) Bladder stone disease in childhood: an epidemiological study. Acta Paediatr Scand 59: 177–180
Hodgkinson A, Williams A (1972) An improved calorimetric procedure for urinary oxalate. Clin Chim Acta 36:127–132
Rajgopal G (1984) Urinary citric acid estimation. Indian J Exp Biol 22:391–392
King EJ, Wooton IDP (1959) Microanalysis in medical biochemistry, 3rd edn. Churchill, London, pp 198–212
Stapleton FB, Noe HN, Jerkins G, Roy S III (1982) Urinary excretion of calcium following an oral calcium loading test in healthy children. Pediatrics 69:594–597
Polansky MS, Kaiser BA, Baluarte HJ (1987) Urolithiasis in childhood. Pediatr Clin North Am 34:683–710
Hymes LC, Warshaw BL (1984) Idiopathic hypercalciuria: renal and absorptive subtype in children. Am J Dis Child 138:176–179
Srivastava RN, Hussainy MAA, Goel RG (1986) Bladder stone disease in children in Afghanistan. Br J Urol 58:374–377
Rizvi SA, Naqvi SA, Hussain ZR (1985) Renal stones in children in Pakistan. Br J Urol 57:618–621
Noe HN, Stapleton FB, Jenkin JR (1983) Clinical experience with pediatric urolithiasis. J Urol 129:1166–1168
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Hari, P., Bagga, A., Vasudev, V. et al. Aetiology of nephrolithiasis in north Indian children. Pediatr Nephrol 9, 474–475 (1995). https://doi.org/10.1007/BF00866731
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DOI: https://doi.org/10.1007/BF00866731