Demographic and clinical characteristics of UK children with advanced CKD, stratified by KRT status (n=1260)
Variable | CKD (not KRT) cohort 0–<16 years (N=199) n (%) | KRT cohort 0–<16 years (N=832) n (%) | ||
Male sex | 128 | 64.3 | 518 | 62.3 |
Age band (years) | ||||
0–5 | 57 | 28.6 | 143 | 17.2 |
6–10 | 60 | 30.2 | 276 | 33.2 |
11–15 | 82 | 41.2 | 413 | 49.6 |
Ethnicity | ||||
White | 114 | 57.3 | 570 | 68.5 |
Asian | 47 | 23.6 | 149 | 17.9 |
Black | 9 | 4.5 | 41 | 4.9 |
Other | 17 | 8.5 | 53 | 6.4 |
Missing | 12 | 6.0 | 19 | 2.3 |
Area-level deprivation quintile (using country-adjusted indices of multiple deprivation) | ||||
1—least deprived | 25 | 12.6 | 116 | 13.9 |
2 | 30 | 15.1 | 143 | 17.2 |
3 | 34 | 17.1 | 155 | 18.6 |
4 | 46 | 23.1 | 183 | 22.0 |
5—most deprived | 61 | 30.7 | 226 | 27.2 |
Missing | 3 | 1.5 | 9 | 1.1 |
CKD stage or KRT modality | ||||
Stage 4 | 121 | 60.8 | ||
Stage 5 | 78 | 39.2 | ||
Haemodialysis | 87 | 10.5 | ||
Peritoneal dialysis | 90 | 10.8 | ||
Kidney transplantation | 655 | 78.7 | ||
Primary kidney disease category | ||||
Familial/hereditary nephropathies | 27 | 13.6 | 105 | 12.6 |
Glomerular disease | 13 | 6.5 | 155 | 18.6 |
Hypertension/renal vascular disease | 2 | 1.0 | 0 | 0.0 |
Miscellaneous renal disorders | 13 | 6.5 | 78 | 9.4 |
Systemic diseases affecting the kidney | 11 | 5.5 | 38 | 4.6 |
Tubulointerstitial disease | 129 | 64.8 | 425 | 51.1 |
Of which congenital anomalies of the kidney and urinary tract (CAKUT) | 129 | 100.0 | 415 | 97.6 |
Non congenital anomalies | 0 | 0.0 | 10 | 2.4 |
Missing | 4 | 2.2 | 31 | 3.7 |
CKD, chronic kidney disease; KRT, kidney replacement therapy.