Table 2

Adjusted log-binomial regression analysis for skill attainment between the CORAL and BASELINE cohorts—complete case analysis

Developmental milestoneCORAL cohort (n=309)
Reached milestone % (n)
BASELINE cohort (n=1629)
Reached milestone % (n)
Adjusted log-binomial regression models# (n=1793)
Relative risk (95% CI)
P value*
Regression diagnostics
Stand aloneYes: 65.7 (203/309)Yes: 66.3 (1080/1629)1.00 (0.91 to 1.11) p=0.99AIC: 1.87
AUC: 0.61
Side stepsYes: 89.6 (277/309)Yes: 86.9 (1416/1629)1.03 (0.98 to 1.09) p=0.18AIC: 1.99
AUC: 0.59
CrawlYes: 97.4 (300/308) Yes: 91.0 (1482/1629) 1.06 (1.03 to 1.09) p<0.01* AIC: 2.00
AUC: 0.61
Stack bricksYes: 72.0 (221/307)Yes: 78.3 (1276/1628)0.93 (0.85 to 1.02) p=0.10AIC: 1.95
AUC: 0.59
Finger feedsYes: 99
(306/309)
Yes: 98.7 (1608/1629)1.00 (0.99 to 1.01) p=0.92AIC: 2.00
AUC: 0.65
PincerYes: 99.7 (307/308)Yes: 99.4 (1620/1629)1.00 (0.99 to 1.01) p=0.72AIC: 2.00
AUC: 0.69
Knows nameYes: 98.7 (305/309)Yes: 98.8 (1610/1629)1.00 (0.98 to 1.01) p=0.64AIC: 2.00
AUC: 0.57
One definite and meaningful wordYes: 76.6 (232/303) Yes: 89.3 (1455/1628) 0.86 (0.80 to 0.92) p<0.01* AIC: 1.99
AUC: 0.65
Finger pointsYes: 83.8 (258/308) Yes: 92.8 (1512/1629) 0.91 (0.86 to 0.96) p<0.01* AIC: 2.00
AUC: 0.67
Waves bye-byeYes: 87.7 (271/309) Yes: 94.4 (1537/1629) 0.94 (0.90 to 0.99) p=0.02* AIC: 2.00
AUC: 0.68
  • *Results highlighted in bold have statistically significant differences between groups.

  • † Log-binomial regression models for each skill, adjusted for age at assessment in days, gender, gestational age in weeks, birth order (first or other) and maternal educational attainment.

  • AIC, Akaike Information Criterion; AUC, area under the curve; BASELINE, Babies After SCOPE: Evaluating the Longitudinal Impact using Neurological and Nutritional Impact; CORAL, Impact of Corona Virus Pandemic on Allergic and Autoimmune Dysregulation in Infants Born During Lockdown.