Table 1

Gram-negative species as percentages of all infant bacteraemia (Gram-negative and Gram-positive) in high-income and low-income/middle-income countries*

High-income countries (n=55 studies)Low-income/middle-income countries (n=90 studies)
Isolates, nProportion (95% CI)Isolates, nProportion (95% CI)
Escherichia coli 502611.7% (9.40 to 14.4%)27587.67% (6.36 to 9.24%)
Klebsiella spp24013.17% (2.07 to 4.84%)591519.0% (16.3 to 22.1%)
Pseudomonas spp6650.70% (0.04 to 1.09%)11272.53% (1.83 to 3.49%)
Enterobacter spp13950.63% (0.31 to 1.29%)9181.18% (0.74 to 1.85%)
Serratia spp4410.15% (0.06 to 0.37%)2370.02% (0.00 to 0.09%)
Proteus spp340.01% (0.00 to 0.05%)1340.04% (0.01 to 0.13%)
Salmonella spp610.00% (0.00 to 0.26%)2150.00% (0.00 to 0.03%)
Citrobacter spp740.01% (0.00 to 0.06%)2490.09% (0.04 to 0.23%)
Haemophilus spp2720.02% (0.01 to 0.10%)380.00% (0.00 to 0.06%)
Neisseria spp190.00% (0.00 to 0.07%)130.00% (0.00 to 0.20%)
Acinetobacter spp3940.14% (0.05 to 0.39%)19963.25% (2.41 to 4.37%)
Moraxella spp30.00% (0.00 to 3.05%)100.00% (0.00 to 3.11%)
Other species or unspecified Gram-negative8680.42% (0.21 to 0.85%)9780.43% (0.22 to 0.83%)
  • *Estimates obtained by random-effects meta-analysis; see online supplemental file 4 for heterogeneity statistics.