Potential to prevent DKA at diagnosis by education on symptoms of diabetes Opportunity for time to adjust to diagnosis Genetic testing for high-risk genes/genetic risk scores possible at birth for use in combination with autoantibodies IAb detectable with fingerprick test, so easy test to administer IAb sensitive and specific May be intervention studies to delay development or prevent T1D in future
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Potential increased anxiety in parents/carers knowing child is at risk High numbers of individuals genetically at risk but who don’t develop T1D If using IAb alone: Treatment of early hyperglycaemia can be challenging No licensed treatment to prevent T1D at present
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