Table 3

Annotated examples illustrating assessment decisions

Drug name (API)WHO suggested formulationStrengthAge group key codeEMLc 2019 assessment (3=yes, 2=maybe, 1=no, 0=n/a)Reasoning for assessment and comments
AmoxicillinPowder for oral liquid125 mg/5 mLN3Doses can be administered in volumes <10 mL
I3
T3
YC3
OC3
250 mg/5 mLN3
I3
T3
YC3
OC3
Solid oral dosage form250 mgN1<6 years cannot swallow conventional-sized tablet/capsule safely
I1
T1
YC1
OC3Can swallow tablet
500 mgN1<6 years cannot swallow conventional-sized tablet/capsule safely
I1
T1
YC1
OC2Dose strength too high for the normal dose
IsoniazidOral liquid50 mg/5 mLN0MFc: infant or child >3 months
I2Dose volume >5 mL for some weight groups
T2
YC2Dose volume >10 mL
OC2
Tablet100–300 mgN0MFc: infant or child >3 months
I1<6 years cannot swallow tablet; no indication that tablet can be crushed
T1
YC1
OC3Adaptable and swallowable across the weight group
Tablet, dispersible100 mgN0MFc: infant or child >3 months
I2Dose strength too high for the lower weight group
T3Dose strength allows for 1–2 tablets
YC3
OC2>3 tablets at higher weight group
Tablet, scored50 mgN0MFc: infant or child >3 months
I1<6 years cannot swallow tablet; no indication that tablet can be crushed
T1
YC1
OC3Adaptable and swallowable across the weight group
  • The category 2 (may be appropriate) include such medicines as those indicated for use for some children within a particular age-group range but not all, for example, only suitable for a child from 10 years within the age group 6–11 years, without any dose accuracy or swallowability issues.

  • BNFc, British National Formulary for children; I, infants; MFc, Model Formulary for children; n, neonates; n/a, not available; OC, older children; T, toddlers; YC, young children.