INTERGROWTH 21st Neurodevelopmental Assessment (INTER-NDA) and Cardiff Vision Test scores
ZIKV exposed (n=68) | ZIKV unexposed (n=63) | |||
INTER-NDA domains | Standardised domain score mean (SD; 95% CI) | Standardised domain score mean (SD; 95% CI) | F* | P value |
Cognition | 63.71 (13.22; 60.57 to 66.86) | 67.17 (12.92; 63.91 to 70.44) | 2.280 | 0.134 |
Fine motor | 91.99 (11.16; 89.25 to 94.95) | 93.83 (11.72; 90.97 to 96.68) | 0.833 | 0.363 |
Gross motor | 92.97 (10.67; 90.31 to 95.63) | 92.77 (11.49; 90.01 to 95.54) | 0.011 | 0.918 |
Language | 66.20 (19.45; 61.43 to 70.95) | 66.10 (20.38; 61.17 to 71.05) | 0.001 | 0.981 |
Positive behaviour | 75.26 (22.13; 70.42 to 79.77) | 78.61 (19.57; 73.45 to 83.18) | 0.830 | 0.364 |
Negative behaviour | 26.59 (26.89; 19.15 to 34.04) | 18.42 (23.40; 10.74 to 26.46) | 2.900 | 0.091 |
Cardiff Vision Tests | ZIKV exposed (n=29) | Unexposed (n=38) | ||
Visual acuity (logMAR) | 0.36 (0.14; 0.31 to 0.41) | 0.26 (0.14; 0.21 to 0.30) | 9.77 | 0.003 |
ZIKV exposed (n=26) | ZIKV unexposed (n=30) | |||
Contrast sensitivity | 42.31 (18.24; 35.17 to 49.74) | 50.89 (17.32; 46.70 to 60.26) | 4.94 | 0.03 |
*With age entered as a covariate.
logMAR, logarithm of the minimum angle of resolution; ZIKV, Zika virus.