Table 1

Verbal reasons why participation in the study was declined

Reasons for declining after being approached onceReasons for declining after being approached two or more times
‘Worried about experiencing nausea’Parents were unable to convince child to participate.
‘Too much to deal with right now’Parent felt that their child already had too many medications.
Worried about risk of probiotic-associated infection.Initially overwhelmed with the new diagnosis. Asked researcher to return later and then declined.
Struggling to persuade the child to take any oral medicines.Child too unwell.
Child dislikes the taste of milk/yoghurts.Mother wanting to participate, father not happy to.
Does not want to take ‘gamble’ of potentially receiving the placebo.Heard from another parent that the probiotic/placebo does not taste nice.