Table 1

Baseline characteristics of children with spirometry and FeNO data (n=465)

Males (%)249 (54)
Mean age in years (95% CI, range)10.9 (10.7 to 11.2, 5–16)
Median deprivation decile of patients according to registered practice (IQR)4 (4 to 6)
Mean BMI (95% CI, range)19.7 (19.3 to 20.1, 11.3–42.6)
Number (%) of children with BMI:
 ≤2nd centile (underweight)12 (2)
 >2nd to <91st centile (healthy)426 (70)
 ≥91st to <98th centile (overweight)80 (13)
 ≥98th centile (obese)93 (15)
Number (%) of children identifying as each ethnic category:
 White365 (78)
 Black16 (3)
 Asian63 (14)
 Mixed21 (5)
Median ACT score in children >11 years (IQR)20 (17–23)
Median CACT score in children ≤11 years (IQR)21 (17–24)
Number of children with ACT/CACT <20 (%)191 (41)
No. of children with ≥1 asthma attacks in preceding 6 months (%)103 (22)
No. of children prescribed ≥1 inhaled corticosteroid in preceding 6 months (%)252 (54)
No. of children prescribed ≥1 SABA inhaler in preceding 6 months (%)332 (71)
No. of children prescribed no ICS or SABA in preceding 6 months (%)106 (23)
Mean asthma medication ratio in children in preceding 6 months (95% CI, range)0.53 (0.49 to 0.56, 0–1)
Mean FEV1 z-score (95% CI)−0.5 (−0.6 to −0.3)
Mean FEV1/FVC z-score (95% CI)−0.7 (−0.8 to −0.6)
Number of children with FEV1, FVC or FEV1/FVC <LLN (%)114 (25)
Number (%) of children with:
 Only FEV1 <LLN10 (2)
 Only FEV1/FVC<LLN only51 (11)
 Only FEV1 and FEV1/FVC<LLN32 (7)
 Only FVC <LLN4 (1)
 Only FEV1 and FVC <LLN13 (3)
 FEV1 and FEV1/FVC and FVC <LLN4 (1)
Median FeNO (ppb) (IQR)23 (11–53)
  • ACT, asthma control test; BMI, body mass index; CACT, childhood asthma control test; FeNO, fraction of exhaled nitric oxide; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; ICS, inhaled corticosteroids; LLN, lower limits of normal; SABA, short acting beta-2 agonist.