Table 1

Baseline clinical characteristics and level of lectin pathway proteins of patients with respectively total ALL (n=151) vs JIA (n=238) and for ALLarthropathy (n=27) vs JIA (n=238)

ALL
N=151
JIA
N=238
P valueALLarthropathy
N=27
P value
Age, years4.6 (2.9–9.3), n=1516.0 (2.9–10.3), n=2380.525.7 (3.6–9.5), n=270.94
Females (n/N)44% (67/151), n=15170% (166/238), n=238<0.001*67% (18/27), n=270.83*
Haemoglobin, g/dL7.9 (5.6–10.0), n=15111.7 (11.3–12.8), n=204<0.0019.7 (7.7–11.1), n=27<0.001
Platelets, ×109/L49 (20–116), n=151331 (287–415), n=203<0.001144 (47–178), n=27<0.001
CRP, mg/L21 (7–51), n=1400 (0–10), n=198<0.00133 (20–97), n=27<0.001
ESR, mm/hour65 (39–104), n=5912 (6–24), n=196<0.00168 (39–99), n=18<0.001
M-ficolin, μg/mL0.65 (0.32–1.21), n=1513.01 (2.43–3.85), n=238<0.0010.73 (0.49–1.33), n=27<0.001
CL-K1, μg/mL0.32 (0.28–0.37), n=1510.28 (0.23–0.34), n=238<0.0010.32 (0.29–0.39), n=27<0.001
MASP-3, μg/mL7.15 (5.44–8.68), n=1518.07 (6.70–9.28), n=238<0.0017.15 (6.06–8.72), n=270.001
  • Values are expressed as median with IQR in parentheses, unless otherwise stated.

  • *P values are calculated by univariate analysis, Wilcoxon rank sum test, except for binary variables calculated by Fisher’s exact test (p*).

  • CL-K1, Collectin-Kidney 1; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; MASP-3, mannan-binding lectin associated serine protease 3.