Table 2

Details of 113 children included in this study with kidney disease on immunosuppressive medication

Median age (IQR)13 years (7–16 years)
Gender51% female, 49% male
Underlying kidney disease and reason for immunosuppression (%)53 kidney transplantation (47%)
30 nephrotic syndrome (27%)
11 SLE (10%)
7 other glomerulonephritis/vasculitis (6%)
2 ANCA associated vasculitis (2%)
2 IgA Nephropathy (2%)
2 IgAVN-HSPN (2%)
2 atypical HUS (2%)
1 C3GN (1%)
1 tubulointersitial nephritis (1%)
1 ESKD with IBD (1%)
1 tuberous sclerosis (1%)
Children on dialysis (%)9 haemodialysis (8%)—four kidney transplant, 1 nephrotic syndrome, 4 glomerulonephritis/ANCA
3 peritoneal dialysis (3%)—1 transplant, 1 nephrotic syndrome, 1 IgAN
Coexistent pulmonary disease (%)4 bacterial/fungal pneumonia (4%)
2 asthma/bronchospasm (2%)
Coexistent cardiac disease (%)4 left ventricular dysfunction/hypertrophy (4%)
Number of children on each type of immunosuppression (%)86 on glucocorticoids (76%)
58 on tacrolimus (51%)
61 on mycophenolate mofetil (54%)
11 having had rituximab (10%)
9 on azathioprine (8%)
8 on ciclosporine (7%)
8 on cyclophosphamide (7%)
5 on sirolimus (4%)
3 having had basiliximab (3%)
3 on everolimus (3%)
2 having had ATG (2%)
2 on eculizumab (2%)
1 having had ofatumumab (1%)
1 having had alemtuzumab (1%)
1 on adalimumab (1%)
1 on levamisole (1%)
  • ANCA, Anti-neutrophil cytoplasmic antibody; ATG, antithymocyte globulin; C3GN, C3 glomerulopathy; ESKD, end-stage kidney disease; HSPN, Henoch-Schönlein purpura nephritis; HUS, haemolytic uraemic syndrome; IBD, inflammatory bowel disease; IgAN, IgA Nephropathy; IgAVN, IgA vasculitis nephritis ; SLE, systemic lupus erythematosus.