Study | Source | Type | Context | Search end | Age | Case definition | Included studies | Total children | Countries of studies | Quality summary |
Mantovani et al 11 | Professional | SR/MA | All | 11 April | NS | NS | 19 | 2855 | China 17, USA, Spain | High |
De Sousa et al 12 | PubMed | SR | All | 6 April | <18 years | RT-PCR+ | 38 | 1124 | China 33, Italy, Iran, Singapore, South Korea, Vietnam | Low |
Yasuhara et al 13 | PubMed | SR | All | 20 June | <18 years | RT-PCR+ | 46 | 114 | China 20, USA 13, 2 Italy, 2 Iran, Korea, Vietnam, Malaysia, Spain, Lebanon, Belgium, UK, Turkey, France | Low |
Hoang et al 14 | PubMed | SR | All | 14 May | ≤21 years | RT-PCR+ | 131 | 7780 | 26 countries; China made up 64% of studies | High |
Cui et al 15 | PubMed | SR/MA | All | 30 April | <18 years | RT-PCR+ | 48 | 5829 | China 43, Singapore, Korea, Spain, USA, Iran | High |
Raba et al 16 | Professional | SR | All; under 1 year | 7 April | <1 year | RT-PCR+ | 18 | 160 | China 17, Vietnam | Medium |
Zhang et al 17 | PubMed | SR/MA | All | 4 May | 0–18 years | ‘Laboratory confirmed COVID-19’ | 46 | 551 | China 35, Iran 2, Italy 3, South Korea, Malaysia, Singapore, Spain, USA, Vietnam | High |
Ma et al 18 | PubMed | SR/MA | Hospitalised | 21 April | NS | RT-PCR+ | 15 | 486 | China | Medium |
Ding et al 19 | Professional | SR/MA | All | 1 April | 0–17 years | RT-PCR+ | 14 | 371 | China | High |
Christophers et al 20 | PubMed | SR | All | 15 May | 1 month to 18 years | RT-PCR+ | 21 | 123 | China 16, USA, Italy 2, Iran, Malaysia | Medium |
Liguoro et al 21 | PubMed | SR | All | 1 May | 0–18 years | ‘Confirmed cases’ | 62 | 7480 | China 49, South Korea 3, Italy 5, Vietnam, Iran, USA, Spain, Malaysia | Medium |
Assaker et al 22 | PubMed | SR/MA | All | 3 May | NS | RT-PCR+ | 28 | 1614 | China 24, Malaysia, Spain, Italy, USA | Medium |
Chang et al 23 | Handsearch | SR/MA | All | 15 March | <18 years | RT-PCR+ | 9* | 93 | China | Medium |
Wang et al 24 | medRxiv | SR/MA | All | 31 March | <18 years | WHO definition | 49† | 1667 | 45 China 1 Singapore, 1 Korea, 1 Vietnam, 1 Iran | High |
Jahangir et al 25 | PubMed | SR | All | 9 April | 0–19 years | NS | 27 | NS | China, South Korea, Spain, USA: numbers not stated | Low |
Pei et al 26 | PubMed | SR | All | 3 March | 0–18 years | RT-PCR+ | 5 | 70 | China | Medium |
Kharoud et al 27 | Europe PMC | SR/MA | All | 15 July | 0–18 years | ‘Laboratory confirmed COVID-19’ | 37 | 668 | China 33, Italy 2, USA, Spain | High |
Wang et al 28 | Europe PMC | SR/MA | Gastrointestinal symptoms only | 10 August | NS | NS | 38 | 3028 | China 21, other countries (not listed) 17 | High |
Search end: all dates are in 2020. Countries: where countries have no number next to them, each country had one included study.
*In Chang et al, 2 studies examined neonates only which were not included in the meta-analysis.
†In Wang et al, only studies with at least 9 cases were included in the meta-analysis.
All, all contexts; MA, meta-analysis; NS, not stated; SR, systematic review.