Table 1

Presentation characteristics of children presenting to PICU with a PCR-positive diagnosis of SARS-CoV-2 infection. Children who presented with a paediatric inflammatory multisystem syndrome were excluded from this description

CharacteristicsPatients (n=11)
Median age, years (IQR)5 (0.4–11.1)
Male, n (%)9 (81)
Ethnicity: Black, Asian and minority ethnic, n (%)4 (36)
PIM3 predicted mortality, n (%)
 <1%5 (42)
 1%–5%4 (36)
 5%–15%1 (9)
 >30%1 (9)
Coexisting disorder, n (%)
 Weight above 91st centile3 (27)
 Cancer1 (9)
 Pre-existing respiratory disease*2 (18)
 Prematurity2 (18)
 Congenital heart disease1 (9)
Median duration of symptoms before admission, no of days (IQR)2 (1.5–3)
Primary presenting symptoms, n (%)
 Cough6 (55)
 Apnoea3 (27)
 Fever10 (90)
 Gastrointestinal (abdominal pain/vomiting/diarrhoea)6 (55)
 Seizures†3 (27)
 SARS-CoV-2 RT-PCR positive on nasopharyngeal aspirate11 (100)
 RSV or influenza RT-PCR positive on nasopharyngeal aspirate0
 Sputum cultures positive for other organisms2 (10)‡
 Blood culture positive for other organisms0
Chest radiography findings, n (%)
 No new parenchymal changes3 (64)
 Parenchymal changes including acute on chronic changes8 (36)
  • *Pre-existing respiratory disorder included chronic lung disease and non-cystic fibrosis bronchiectasis.

  • †Two of the children presented had previously defined epilepsy.

  • ‡Equivocal growth of Staphylococcus aureus and Candida albicans.

  • PICU, paediatric intensive care unit; PICU, paediatric intensive care unit; PIM3, paediatric index of mortality version 3; RSV, respiratory syncytial virus; RT-PCR, reverse transcription polymerase chain reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.