Statistical measures of non-treponemal titres before treatment and maternal antisyphilis treatment during pregnancy as predictions for CS
| Measure | AUC (95% CI) | Cut-off | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | Youden’s index |
| Maternal non-treponemal titres before treatment | 0.80 (0.72 to 0.87) | 1:6 | 76.9 (63.7 to 90.1) | 78.7 (76.7 to 80.8) | 8.5 (5.6 to 11.4) | 99.3 (98.8 to 99.7) | 0.56 |
| Treatment during pregnancy | 0.79 (0.72 to 0.86) | 0.5 | 69.2 (54.7 to 83.7) | 88.7 (87.1 to 90.3) | 13.6 (8.8 to 18.3) | 99.1 (98.6 to 99.6) | 0.58 |
AUC, area under the curve; CS, congenital syphilis; NPV, negative predicted value; PPV, positive predicted value.