Table 3

Statistical measures of non-treponemal titres before treatment and maternal antisyphilis treatment during pregnancy as predictions for CS

MeasureAUC
(95% CI)
Cut-offSensitivity
(95% CI)
Specificity
(95% CI)
PPV
(95% CI)
NPV
(95% CI)
Youden’s index
Maternal non-treponemal titres before treatment0.80 (0.72 to 0.87)1:676.9 (63.7 to 90.1)78.7 (76.7 to 80.8)8.5 (5.6 to 11.4)99.3 (98.8 to 99.7)0.56
Treatment during pregnancy0.79 (0.72 to 0.86)0.569.2 (54.7 to 83.7)88.7 (87.1 to 90.3)13.6 (8.8 to 18.3)99.1 (98.6 to 99.6)0.58
  • AUC, area under the curve; CS, congenital syphilis; NPV, negative predicted value; PPV, positive predicted value.