Diagnostic accuracy of LAMP testing on oropharyngeal swabs for predicting meningococcal disease
Index test | Meningococcal disease | Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) | Positive likelihood ratio (95% CI) | Negative likelihood ratio (95% CI) | |
Present | Absent | |||||||
LAMP positive | 5 | 9 | 1.00 (0.46 to 1.00) | 0.97 (0.93 to 0.98) | 0.36 (0.14 to 0.64) | 1.00 (0.98 to 1.00) | 28.3 (14.9 to 53.8) | N/A |
LAMP negative | 0 | 246 |
LAMP, loop-mediated isothermal amplification.