Table 2

Marginal effects of morbidity on 6-month hospital costs (imputed data set)

Morbidity categoryCoefficientP valueMarginal effect (95% CI)
Extracorporeal life support1.326<0.001£66 784 (£40 609 to £103 539)
Multiple morbidity (except ECLS)0.941<0.001£37 697 (£25 971 to £52 167)
Unplanned reoperation0.667<0.001£22 903 (£9598 to £41 456)
Feeding problems0.555<0.001£17 927 (£8057 to £30 824)
Necrotising enterocolitis0.5230.04£16 592 (£599 to £42 924)
Acute neurological event0.4580.21£14 042 (−£5424 to £53 753)
Renal support0.3820.03£11 241 (£936 to £25 781)
Postsurgical infection morbidity0.3470.17£10 025 (−£3266 to £31 779)
Prolonged pleural effusion0.2700.05£7483 (£3 to £17 289)
Major adverse event0.1890.32£5030 (−£4119 to £18 359)
Observations from imputed data, n=666
  • In every case the regression model was a generalised linear model with gamma family and log link. The marginal effects are the change in costs versus the omitted category (no morbidities). Data include values imputed using multiple imputation. Costs are in 2016/2017 UK£. Controls were also included in every model for: age; weight by age; whether or not the patient had a pre-existing congenital morbidity, pre-existing severe illness or Down’s syndrome; underlying diagnosis prompting cardiac surgery; type of cardiac procedure performed; whether or not the patient died within 6 months; and study centre.

  • ECLS, extracorporeal life support.