Summary of all articles
| Study type | No. of studies | No. of ADRs, n (%) | No. of patients, n (%) |
| RCTs | 22 | 423 (37.2) | 2462 (43.1) |
| Prospective cohort studies | 19 | 357 (31.4) | 2397 (41.9) |
| Retrospective cohort studies | 7 | 75 (6.6) | 730 (12.8) |
| Case–control | 1 | 3 (0.3) | 40 (0.7) |
| Case series | 2 | 23 (2.0) | 23 (0.4) |
| Case report | 61 | 255 (22.5) | 65 (1.1) |
| Total | 112 | 1136 | 5717 |
ADRs, adverse drug reactions; RCT, randomised controlled trial.