Table 3

Mortality during the index hospital admission (n=5131; multivariable analysis with multiple imputation)

Relative risk (RR) (95% CI)P value
Ethnicity (reference: white)
 British Asian 1.55 (1.07 to 2.26) 0.020
 Black British1.39 (0.81 to 2.38)0.233
 All other 1.64 (1.05 to 2.57) 0.031
Sex (reference: boys)
 Girls1.06 (0.81 to 1.40)0.675
Area deprivation (IMD) quintile (reference: quintile 5=least deprived)
 Quintile 41.04 (0.63 to 1.71)0.879
 Quintile 30.87 (0.52 to 1.46)0.610
 Quintile 21.33 (0.86 to 2.06)0.203
 Quintile 1: most deprived0.94 (0.60 to 1.48)0.796
Birth gestation (reference: term birth ≥37 weeks’ gestation)
 Preterm (<37 weeks)1.25 (0.57 to 2.77)0.569
Prenatal diagnosis (reference: not prenatally diagnosed)
 Prenatal diagnosis 1.92 (1.41 to 2.64) <0.001
Non-cardiac comorbidities/procedure-related clinical status (reference: no comorbidities)
 Congenital anomalies 1.58 (1.12 to 2.24) 0.010
 Acquired comorbidities 1.58 (1.04 to 2.41) 0.033
 Neurodevelopmental problems 0.41 (0.18 to 0.94) 0.035
 Preprocedure deterioration 1.52 (1.12 to 2.06) 0.008
Index admission
Age (per week increase) 0.98 (0.96 to 0.99 0.020
 Weight z-score0.97 (0.80 to 1.19)0.769
Primary cardiac diagnoses (reference: VSD)
 Hypoplastic left heart syndrome 8.27 (3.61 to 18.96) <0.001
 Functionally univentricular heart 6.34 (2.79 to 14.43) <0.001
 Common arterial trunk 6.74 (2.62 to 17.35) <0.001
 TGA with VSD/DORV-TGA type1.96 (0.75 to 5.08)0.168
 Interrupted aortic arch 6.71 (2.42 to 8.58) <0.001
 TGA+IVS0.81 (0.17 to 3.83)0.790
 Pulmonary atresia+IVS 6.45 (2.71 to 15.36) <0.001
 Pulmonary atresia+VSD 6.32 (2.68 to 14.94) <0.001
 Miscellaneous primary cardiac diagnoses 2.88 (1.14 to 7.25) 0.025
 Complete AVSD1.96 (0.80 to 4.85)0.143
 Fallot’s tetralogy/DORV Fallot type2.25 (0.91 to 5.57)0.078
 Aortic valve stenosis (isolated) 7.18 (2.80 to 18.42) <0.001
 Tricuspid valve abnormality 5.99 (1.84 to 19.50) 0.003
 Mitral valve abnormality 8.01 (2.81 to 22.77) <0.001
 TAPVC0.71 (0.09 to 5.75)0.752
 Aortic arch obstruction1.14 (0.42 to 3.09)0.794
 Pulmonary stenosis1.11 (0.24 to 5.09)0.892
 ASD 5.89 (1.81 to 19.16) 0.003
 PDA0.93 (0.13 to 6.92)0.945
 Miscellaneous congenital terms Too few events
  • Results from a multivariable Poisson model with 20 imputed datasets. Bold text indicates significant result at P<0.05.

  • AVSD, atrioventricular septal defect; ASD, atrial septal defect; DORV, double outlet right ventricle; IMD, Index of Multiple Deprivation; IVS, intact ventricular septum; PDA, persistent ductus arteriosus; TGA, transposition of the great arteries; TAPVC, totally anomalous pulmonary venous connection; VSD, ventricular septal defect.