Table 3

Injury by cardiac physiology group. Numbers in brackets refer to 95% CI. Altered streaming includes infants with TGA and truncus arteriosus. Left-sided lesions includes CoA and HLHS. Right-sided lesions includes TOF, pulmonary atresia, pulmonary stenosis and tricuspid atresia. P value reflects distribution across cardiac physiology groups compared using χ2 tests

Brain injury typeCardiac physiology group
Altered streamingLeft-sided lesionRight-sided lesionTotalP value
n%n%n%n%
WMI: all1132 (19 to 49)536 (16 to 61)732% (16 to 53)2333 (23 to 44)0.967
WMI category0.734
 Mild515 (6 to 30)321 (8 to 48)627 (13 to 48)1420 (12 to31)
 Moderate39 (3 to 23)214 (4 to 40)15 (1 to 22)69 (4 to 17)
 Severe13 (1 to 15)00 (0 to 22)00 (0 to 15)11 (0.3 to 8)
 WMI with infarct26 (2 to 19)00 (0 to 22)00 (0 to 15)23 (1 to 10)
Arterial ischaemic stroke39 (3 to 23)00 (0 to 22)00 (0 to 15)34 (1 to 12)0.190
Cerebellar haemorrhage26 (2 to 19)214 (4 to 40)29 (3 to 28)69 (4 to 17)0.636
Parenchymal haemorrhage00 (0 to 10)00 (0 to 22)00 (0 to 15)00 (0 to 5)1.000
Venous sinus thrombosis00 (0 to 10)00 (0 to 22)00 (0  to 15)00 (0 to 5)1.000
Subdural haemorrhage1235 (21 to 52)643 (21 to 67)523 (10 to 43)2333 (23 to 44)0.417
Total34142270
  • CoA,  coarctation of the aorta; HLHS, hypoplastic left heart syndrome; TOF, tetralogy of Fallot; WMI, white matter injury.