Table 2

Multivariate analysis of demographic and clinical characteristics associated with treatment abandonment

FeatureCategoryPatients not abandoning treatment
n (%)
Patients abandoning treatment
n (%)
OR (95% CI)P value
Age (years)1–92058 (97.9)44 (2.1)
≥10267 (95.4)13 (4.6)1.07 (0.51 to 2.16)0.8539
<124 (96)1 (4.0)1.06 (0.06 to 5.85)0.9561
Risk group*Low1585 (98.5)24 (1.5)
Standard/high764 (95.7)34 (4.3)2.62 (1.43 to 4.77)0.0016
MRD, day 19Negative1085 (98.3)19 (1.7)
Positive1264 (97.0)39 (3.0)1.09 (0.58 to 2.10)0.7825
MRD, day 46†Negative2001 (98.3)35 (1.7)
Positive348 (93.8)23 (6.2)3.57 (1.90 to 6.74)0.0007
RegionHigh income1336 (98.1)26 (1.9)
Middle income765 (97.9)16 (2.1)1.11 (0.58 to 2.08)0.7461
Low income248 (93.9)16 (6.1)3.70 (1.89 to 7.05)0.0008
  • *Initial risk determined at diagnosis.

  • †Patients without day 46 MRD data were excluded.

  • MRD, minimal residual disease.