Treatment delivery by group
| Variables | 10 mL/kg | 20 mL/kg |
| Patients, n | 39 | 34 |
| Number of study boluses delivered, n (%) of patients | ||
| 0 | 3 (7.7) | 0 (0.0) |
| 1 | 23 (59.0) | 25 (73.5) |
| 2 | 8 (20.5) | 6 (17.6) |
| 3 | 3 (7.7) | 1 (2.9) |
| 4 or more | 2 (5.1) | 2 (5.9) |
| Total volume of study fluid received during the first hour (mL/kg)* | ||
| Mean (SD) | 13.5 (8.0) | 20.7 (8.3) |
| Total volume of study fluid received during the intervention period (mL/kg)* | ||
| Mean (SD) | 14.5 (11.1) | 25.7 (12.0)* |
| Total number of boluses delivered† | 58 | 48 |
| Volume of study bolus, n (%) of boluses | ||
| <10 mL/kg‡ | 2 (3.4) | 3 (6.3) |
| 10 mL/kg† | 56 (96.6) | 5 (10.4) |
| 20 mL/kg† | 0 (0.0) | 40 (83.3) |
| Timing of delivery of study bolus, n (%) of boluses§ | ||
| ≤15 min | 38 (80.9) | 30 (68.2) |
| 16–20 min | 7 (14.9) | 5 (11.4) |
| 21–30 min | 2 (4.3) | 1 (2.3) |
| >30 min | 0 (0.0) | 8 (18.2) |
| Delivery of study bolus with 15 min by age group, n (%) of boluses‡ | ||
| <1 year | 24/27 (88.9) | 22/29 (75.9) |
| 1 to <2 years | 7/9 (77.8) | 2/3 (66.7) |
| 2 to <5 years | 6/7 (85.7) | 2/4 (50.0) |
| ≥5 years | 1/4 (25.0) | 4/8 (50.0) |
| Study fluid boluses delivered at the correct volume and within 15 min, n (%) of boluses‡ | ||
| No | 10 (21.3) | 20 (45.5) |
| Yes | 37 (78.7) | 24 (54.5) |
*P<0.001 (t-test).
†All study boluses were of normal saline except 4 of plasmalyte and 4 of Hartmann’s solution.
‡±10%.
§Timing of delivery not reported for 15 boluses (11 in 10 mL/kg group, 4 in 20 mL/kg group).