OR for different wheezing trajectories (early-remittent wheeze, late wheeze and persistent/relapsing wheeze) by gestational age group
| Asthma trajectories | Gestational age groups | ||||
| <32 weeks; very preterm | 32–33 weeks; moderate preterm | 34–36 weeks; late preterm | 37–38 weeks; early term | 39–41 weeks; full term | |
| No wheeze (no wheezing at 3, 5, 7 and 11) | n=50 (41.3%) | n=58 (55.4%) | n=349 (61.0%) | n=1317 (66.1%) | n=4784 (67.4%) |
| Early-remittent wheeze (only wheeze at 3 and/or 5) | n=27 (25.2%) | n=24 (19.1%) | n=119 (19.4%) | n=324 (16.7 %) | n=1072 (15.5%) |
| Relative risk ratio (95% CI)* | 2.72 (1.49 to 4.96) | 1.52 (0.89 to 2.60) | 1.38 (1.10 to 1.74) | 1.11 (0.94 to 1.29) | 1 |
| Late wheeze (only wheeze at 7 and/or 11) | n=13 (8.7%) | n=11 (7.9%) | n=26 (5.7%) | n=135 (5.6%) | n=481 (6.8%) |
| Relative risk ratio (95% CI)* | 2.19 (1.04 to 4.62) | 1.42 (0.71 to 2.86) | 0.91 (0.58 to 1.42) | 0.85 (0.66 to 1.09) | 1 |
| Persistent/relapsing wheeze (wheeze in early life at ages 3 and/or 5, and later in life at ages 7 and/or 11) | n=29 (24.8%) | n=19 (17.6%) | n=80 (13.9%) | n=239 (11.6%) | n=761 (10.3%) |
| Relative risk ratio (95% CI)* | 4.30 (2.33 to 7.91) | 2.06 (1.16 to 2.69) | 1.45 (1.09 to 1.94) | 1.15 (0.97 to 1.38) | 1 |
Unweighted counts and survey-weighted proportions reported.
*Adjusted for child’s sex, ethnicity and age at interview; family history of asthma, household’s national statistics socioeconomic classification, maternal age at delivery, lone parent family and alcohol use during pregnancy.