Clinical course and bacteriology
| Case | Presented | Age (months), sex | Disease | Lowest eGFR (mL/min/1.73 m2) | DAT | Admission duration (days) | Renal replacement therapy, duration (days) | Serotype | Vaccine | Vaccine failure |
| 1 | December 2001 | 12, F | Meningitis, bacteraemia | 9 | Negative | 18 | PD, 7 | 14 | Nil | No |
| 2 | May 2007 | 20, F | Pneumonia/empyema | 10 | Positive (C3d) | 12 | PD, 7 | 3 | PCV7 | No |
| 3 | April 2009 | 19, F | Pneumonia/empyema, bacteraemia | 5 | Positive (IgG, C3d) | 36 | PD, 428 | 19A | PCV7 | No |
| 4 | March 2010 | 11, M | Pneumonia/empyema | 8 | Positive (IgG, C3d) | 26 | PD, 19 | 19A | PCV7 | No |
| 5 | August 2011 | 12, M | Pneumonia/empyema | 15 | Positive (IgG, C3d) | 15 | PD, 2 | 19A | PCV7 | No |
| 6 | September 2012 | 12, M | Pneumonia/empyema | 19 | – | 17 | Nil | 19A | PCV13 | Yes |
| 7 | November 2013 | 17, M | Pneumonia, bacteraemia | 35 | Negative | 9 | Nil | 7F | PCV13 | Yes |
| 8 | September 2014 | 12, F | Pneumonia/empyema, bacteraemia | 6 | Negative | 25 | PD, 23 | 19A | Nil | No |
| 9 | April 2016 | 11, M | Pneumonia/empyema | 20 | – | 15 | CVVH, 2 | 3 | PCV13 | Yes |
| 10 | April 2016 | 7, F | Presumed meningitis, bacteraemia | 10 | Negative | 19 | PD, 4 | 10A | PCV13 | No |
| 11 | May 2016 | 18, M | Pneumonia/empyema, bacteraemia | 15 | Negative | 14 | CVVH, 4 | 19A | PCV13 | Yes |
C3d, complement factor 3d; CVVH, continuous veno-venous haemofiltration; DAT, direct antiglobulin test; eGFR, estimated glomerular filtration rate; IgG, immunoglobulin G; PCV, pneumococcal conjugate vaccine (7-valent or 13-valent); PD, peritoneal dialysis.