Annual neonatal mortality in total live births and SNJ and the incidence of SNJ with different severity in Taiwan
| Year | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 |
| Annual births† (n) | 305 312 | 260 354 | 247 530 | 227 070 | 216 419 | 205 854 | 204 459 | 204 414 | 198 733 | 191 310 | 166 886 |
| Mortality† (n) (%)* | 1048 (0.34) | 878 (0.34) | 755 (0.31) | 638 (0.28) | 628 (0.29) | 620 (0.30) | 559 (0.27) | 597 (0.29) | 548 (0.28) | 459 (0.24) | 429 (0.26) |
| SNJ (n) (%)*‡ | 17 877 (5.86) | 17 699 (6.80) | 19 295 (7.80) | 19 200 (8.46) | 22 253 (10.28) | 22 809 (11.08) | 24 413 (11.94) | 25 082 (12.27) | 25 590 (12.88) | 25 399 (13.28) | 22 929 (13.74) |
| SNJ mortality (n) (%)* | 92 (0.51) | 81 (0.46) | 55 (0.29) | 63 (0.33) | 60 (0.27) | 48 (0.21) | 48 (0.20) | 66 (0.26) | 53 (0.21) | 44 (0.17) | 59 (0.26) |
| Level of severity§ | |||||||||||
| Phototherapy (n) (%)*¶ | 12 335 (69) | 12 610 (71.25) | 14 179 (73.49) | 14 046 (73.16) | 15 591 (70.06) | 16 136 (70.74) | 17 152 (70.26) | 17 211 (68.62) | 17 088 (66.78) | 17 080 (67.25) | 15 451 (67.39) |
| Intensive phototherapy (n) (%)*¶ | 2498 (13.97) | 2706 (15.29) | 2900 (15.03) | 3164 (16.48) | 4242 (19.06) | 4622 (20.26) | 5003 (20.49) | 6023 (24.01) | 6588 (25.74) | 6521 (25.67) | 6069 (26.47) |
| ET (n) (%)*¶ | 96 (0.54) | 67 (0.38) | 67 (0.35) | 55 (0.29) | 40 (0.18) | 49 (0.21) | 23 (0.09) | 20 (0.08) | 15 (0.06) | 23 (0.09) | 18 (0.08) |
*Trend in proportions: P<0.001.
†Source: Department of Household Registration database, Ministry of Health and Welfare, Republic of China.
‡Number of SNJ cases/number of annual live births.
§Severity of SNJ was categorised according to intervention, which includes phototherapy, intensive phototherapy and ET.
¶Number of SNJ cases with each intervention/number of total SNJ cases.
ET, exchange transfusion; NJ, neonatal jaundice; SNJ, significant neonatal jaundice.