Table 1

Baseline characteristics of patients by treatment group

Characteristics10 mL/kg
(n=39)
20 mL/kg
(n=34)
Age (months)
 Median (IQR)11 (1–35)2 (1–17)
Gender, n (%)
 Male24 (61.5)18 (52.9)
 Female15 (38.5)16 (47.1)
Weight (kg)
 Median (IQR)9 (5–13)5 (4–10)
Shock criteria met, n (%)
 CRT* only30 (76.9)30 (88.2)
 Hypotension only2 (5.1)2 (5.9)
 CRT* and hypotension1 (2.6)2 (5.9)
 Neither6 (15.4)0 (0.0)
Systolic BP (mm Hg)
 Median (IQR)102 (91–114)104 (89–115)
CRT (s)
 Median (IQR)3 (3–4)3 (3–4)
PIM2r (2016) score (%)
 Median (IQR)2.1 (1.6–2.7)2.0 (1.6–2.5)
Infection confirmed, n (%)
 No19 (48.7)17 (50.0)
 Yes20 (51.3)17 (50.0)
Organism
 Bacterial, n (%)5 (31.3)8 (50.0)
  Escherichia coli1 (6.3)4 (25.0)
  Enterococcus faecalis2 (12.5)0 (0.0)
  Group A streptococcus1 (6.3)1 (6.3)
  Group B streptococcus0 (0.0)1 (6.3)
  Staphylococcus aureus1 (6.3)0 (0.0)
  Meningococcus0 (0.0)1 (6.3)
  Gram-positive coccus (unspecified)0 (0.0)1 (6.3)
 Viral, n (%)10 (62.5)8 (50.0)
  Respiratory syncytial virus 5 (31.3)3 (18.8)
  Rhinovirus2 (12.5)3 (18.8)
  Influenza A0 (0.0)1 (6.3)
  Metapneumovirus1 (6.3)0 (0.0)
  Enterovirus1 (6.3)1 (6.3)
  Rotavirus1 (6.3)0 (0.0)
 Others, n (%)1 (6.3)0 (0.0)
  Falciparum malaria1 (6.3)0 (0.0)
  • *CRT≥3 s.

  • BP, blood pressure; CRT, capillary refill time; PIM2r, Paediatric Index of Mortality, recalibrated version.