Table 4

Potential outcome measures by treatment group

Potential outcome measures10 mL/kg
(n=39)
20 mL/kg
(n=34)
Difference
(95% CI)
Hospital mortality, n/N (%)0/39 (0.0)0/34 (0.0)NA
Length of hospital stay (days), median (IQR) (N)4 (3–7) (39)5 (4–8) (34)−1 (−2.5 to 0.5)
Transferred to PICU, n/N (%)10/39 (25.6)11/34 (32.4)−6.7 (−27.6 to 14.1)
Length of stay in PICU (hours), median (IQR) (N)45 (18–143) (10)119 (52–228) (11)−65 (−171 to 41)
Days alive and free of PICU up to 30 days postrandomisation, mean (SD) (N)28.9 (2.4) (39)27.9 (3.6) (34)1.0 (−0.4 to 2.4)
Receipt of mechanical ventilation, n/N* (%)4/36 (11.1)8/32 (25.0)−13.9 (−32.1 to 4.3)
Duration of mechanical ventilation (days), median (IQR) (N)*6 (4–8) (4)5.5 (4–8.5) (8)0 (−5.9 to 5.9)
Days alive and free of mechanical ventilation up to 30 days postrandomisation, mean (SD) (N)*29.3 (2.1) (36)28.5 (2.7) (32)0.8 (−0.4 to 2.0)
Receipt of inotropes, n/N* (%)1/36 (2.8)5/32 (15.6)−12.8 (−26.5 to 0.8)
Mortality at 30 days postrandomisation, n/N (%)0/39 (0.0)0/34 (0.0)NA
  • *Organ support data missing for three patients in the 10 mL/kg group and two patients in the 20 mL/kg group transferred to PICUs not participating in the pilot trial.

  • NA, not available; PICU, paediatric intensive care unit.