Child demographics, clinical characteristics and neurological function at 6–7 years by trial arm for surviving children with questionnaire data
| Control group (n=70) | Hypothermia group (n=75) | P value | |
| Baseline demographics and characteristics at trial entry | |||
| Male sex, n (%) | 41 (59) | 47 (63) | 0.61 |
| Missing | 0 | 0 | |
| Age (years) | |||
| Median (IQR) | 6.3 (6.1–6.7) | 6.3 (6.1–6.8) | 0.36 |
| Missing | 3 | 1 | |
| Gestational age (weeks) | |||
| Median (IQR) | 40.1 (39–41) | 40.2 (39.3–41.4) | 0.48 |
| Missing | 10 | 7 | |
| Birth weight (g) | |||
| Median (IQR) | 3400 (3200–3850) | 3460 (3172–3828) | 0.80 |
| Missing | 0 | 0 | |
| Delivery complications, n (%) | 52 (75) | 57 (77) | 0.82 |
| Missing | 1 | 1 | |
| Apgar score ≤5 at 10 min, n (%) | 42 (74) | 41 (71) | 0.72 |
| Missing | 13 | 17 | |
| Outcomes at 6–7 years | |||
| Normal neurological function, n (%) | 35 (50) | 50 (67) | 0.04 |
| Missing | 0 | 0 | |
| IQ ≥85, n (%) | 43 (64) | 59 (79) | 0.06 |
| Missing | 3 | 0 | |
| Overall disability*, n (%) | |||
| None or mild | 42 (60) | 59 (81) | 0.006 |
| Moderate or severe | 28 (40) | 14 (19) | |
| Missing | 0 | 2 | |
IQR Inter-quartile range; IQ Intelligence Quotient; *Overall disability: mild disability (an IQ score of 70–84, level 1 gross motor function (is able to walk independently but may have some gait abnormalities), or abnormality in one or both eyes with normal or nearly normal vision); moderate disability (an IQ score of 55–69, level 2 or 3 gross motor function (has minimal ability to perform gross motor skills or requires assistance with walking) or moderately reduced vision); severe disability (an IQ score of <55, level 4 or 5 gross motor function (needs adaptive seating or has severely limited mobility) or no useful vision).