Remission after stopping ATD | Relapse after stopping ATD | P value | |

Number (F:M) | 20 (18F:2M) | 15 (13F:2M) | |

Age at diagnosis, median (range) | 12.2 (3.7–15.6) (n=20) | 9.3 (4.3–15.8) (n=15) | 0.29 |

Graves’s disease: Hashimoto’s thyroiditis | 10:10 | 12:3 | 0.06 |

Goitre at diagnosis | None (n=5) Small (n=7) Moderate (n=3) Large (n=1) Not specified (n=4) | Small (n=8) Moderate (n=4) Not specified (n=3) | - |

Type of initial ATD treatmentDT BR
| DT: 13 BR:7 | DT: 9 BR: 6 | |

Median (range) fT4 (pmol/L) at diagnosis (n=34) | 44.0 (4.8–105.0) (n=19) | 44.7 (27.8–124.1) (n=15) | 0.27 |

Median (range) TT4 (nmol/L) at diagnosis (n=34) | 293 (35-733) (n=19) | 236 (19–733) (n=15) | <0.01 |

Mean/median (range) TRAB (U/L) at diagnosis (n=25) | 15/4 [<3–59) (n=15) | 22, 16 [<3–67) (n=10) | 0.30 |

Where the data for a given row are fewer than the total patient number (35), the available number is given as (n=) in the left-hand column.

BR, block and replace; DT, dose titration; fT4, free thyroxine; TRAB, TSH receptor antibody; TT4, total T4.