Table 1

Demographics of included Outpatient Parenteral Antimicrobial Therapy episodes with analyses of the preintervention and postintervention study periods (n=407)

Preintervention period (n=188)Postintervention period (n=219)p Value
Median age on admission to OPAT (years)5.4 (1.5–10.6)4.3 (1.8–9.8)0.804*
Gender: male (%)98 (52.1)118 (53.9)0.724†
Median duration of OPAT (days) (IQR)6 (2–11)5 (2–10)0.098*
Median time from hospital admission to discharge home with OPAT (days) (IQR)3 (1–7)3 (1–6)0.051*
Median total length of antimicrobial treatment (days) (IQR)10.5 (5–18)8 (4–15)0.069*
No. of formal ID consults (%) (n=395)47/188 (25.0)56/207 (27.1)0.643†
Monitoring if on OPAT ≥7 days (n=180) (%)44/93 (47.3)71/87 (81.6) <0.001
OR 4.94
95% CI 2.51 to 9.74
Abnormalities if laboratory monitoring performed (%)(n=115)8/44 (18.2)16/71 (22.5)0.708†
PICC or midline complications (n=167) (%)5/83 (6.02)15/84 (17.86) 0.019
OR 3.39
95% CI 1.17 to 9.81
Unplanned readmission to hospital while receiving OPAT (n=407) (%)28 (14.9)16 (7.3) 0.014
OR 0.45
95% CI 0.24 to 0.86
  • *Mann-Whitney U test.

  • †Pearson’s χ2 test.

  • Statistically significant p-values (<0.05) are provided in bold.

  • ID, infectious diseases; OPAT, Outpatient Parenteral Antibiotic Therapy; PICC, peripherally inserted central catheter.