Table 1

AEFIs by age at immunisation and expressed in terms of numbers of doses of routine or 4CMenB vaccines

AgeEraDoses administered*Probable/ possible AEFIsAEFIs per 1000 dosesOR (95% CI)p Value
2 monthsPre-4CMenB14 584151.033.3 (1.7 to 6.3)<0.001
Post-4CMenB7381253.39
3 monthsPre-4CMenB14 74170.471.7 (0.6 to 5.1)0.380
Post-4CMenB738160.81
3 months
(catch up)
NA59246.76
4 monthsPre-4CMenB14 08620.148.0 (1.7 to 38.5)0.005
Post-4CMenB616871.13
2 and 4 months combinedPre-4CMenB28 670170.594.0 (2.2 to 7.2)<0.001
 Post-4CMenB13 549322.36
  • *Doses refers to combination diphtheria toxoid, tetanus toxoid, acellular pertussis, inactivated polio and Haemophilus influenzae type b at 2, 3 and 4 months in the pre-4CMenB era, 3 months on the post-4CMenB era, 4CMenB at 2 and 4 months and 3 months (catch up) in the post-4CMenB era.

  • 4CMenB, capsular group B meningococcal vaccine; AEFI, adverse events following immunisation; NA, not applicable.