General characteristics of 165 children admitted with Plasmodium falciparum malaria
| Characteristics | Cases (n=55) | Controls (n=110) | p Value |
|---|---|---|---|
| Boys, n (%) | 29/55 (52.7%) | 65/110 (59.1%) | 0.44* |
| Age (months), median (IQR) | 94 (33–147) | 87 (39–134) | 0.96 |
| Infants (<3 years old), n (%) | 14/55 (25.5%) | 20/110 (18.2%) | 0.28* |
| Born in countries with endemic malaria, n (%) | 8/55 (14.5%) | 13/110 (11.8%) | 0.63* |
| Duration of overseas travel (days), median (IQR) (missing data n=16) | 46 (29–90) | 51 (31–62) | 0.96† |
| Duration of symptoms before admission (days), median (IQR) (missing data n=27) | 4 (2–6) | 2 (1–5) | 0.04† |
| Antimalarial chemoprophylaxis, n (%) | 0.40‡ | ||
| Appropriate | 3/52 (5.8%) | 10/104 (9.6%) | |
| Inappropriate and/or low compliance | 22/52 (42.3%) | 53/104 (51.0%) | |
| None | 27/52 (51.9%) | 43/104 (41.4%) | |
| Duration of PICU stay (days), median (IQR) | 2 (1–3) | – | |
| Duration of hospital stay (days), median (IQR) | 6 (4–7) | 1 (0–2) | <0.01† |
Cases: Children hospitalised in paediatric intensive care units (PICUs); Controls: Children not hospitalised in PICUs.
*χ2 test.
†Wilcoxon rank sum test.
‡Fisher's exact test.