Characteristic | Number (%) N=43 |
---|---|
Referred from primary clinic | 5 (12) |
Referred from district hospital | 38 (88) |
Female | 17 (40) |
Median age; years (IQR) | 3 (1.5–6.5) |
Children ≤1 year | 4 (16) |
Weight <3rd percentile for age | 9 (21) |
Days from DR-TB diagnosis to KDH examination; median (IQR) | 80 (60–117) |
TB-related findings | |
Signs or symptoms suggestive of TB | 0 |
Abnormal chest radiograph | 0 |
Previous TB treatment* | 18 (42) |
Presently on TB treatment | 15 (35) |
Previous TB treatment and presently on TB treatment | 8 (19) |
Reported contact with infectious MDR-TB source case | 3 (7) |
Respiratory specimen Mycobacterium tuberculosis positive | 42 (98) |
Extrapulmonary specimen (FNAB) M. tuberculosis positive | 1 (2) |
HIV status | |
HIV unknown | 2 (5) |
HIV infected | 7/41 (17) |
On antiretroviral therapy | 4/7 (57) |
Drug-resistance profile | |
Monoresistant | 9 (21) |
Isoniazid monoresistant | 2 (5) |
Rifampicin monoresistant | 7 (16) |
MDR | 29 (68) |
Pre-XDR | 1 (2) |
XDR | 4 (9) |
*Previous TB treatment refers to any TB episode for which the child received treatment during the course of their life (excluding the current episode).
FNAB, fine needle aspiration biopsy; KDH, King Dinuzulu Hospital (specialist TB hospital); MDR, multidrug resistance; resistance to isoniazid and rifampicin; Pre-XDR-TB, MDR-TB with resistance to either a fluoroquinolone or an aminoglycoside, but not both; TB, tuberculosis; XDR-TB, MDR-TB with resistance to both a fluoroquinolone and an aminoglycoside.