Table 3

Primary care presentation rate (per 100 person-months) for each symptom group from CPRD-linked tumour registrations before intracranial tumour diagnosis in patients aged 0–24 years, England, 1989–2006

(A) By age at presentation
Age at presentation0–4 years5–11 years12–18 years19–24 years
Length of observation (person-months)4945.86062.13342.01228.5
Symptom groupCountRate95% CICountRate95% CICountRate95% CICountRate95% CI
Headache50.100.04 to 0.24390.640.47 to 0.88531.591.21 to 2.08302.441.71 to 3.49
Raised ICP210.420.28 to 0.65110.180.10 to 0.3390.270.14 to 0.5260.490.22 to 1.09
Convulsions100.200.11 to 0.38170.280.17 to 0.45100.300.16 to 0.56292.361.64 to 3.40
Visual disturbance240.490.33 to 0.72210.350.23 to 0.53160.480.29 to 0.7880.650.33 to 1.30
Focal deficits140.280.17 to 0.48130.210.12 to 0.37110.330.18 to 0.5970.570.27 to 1.20
Growth or endocrine50.100.04 to 0.24100.160.09 to 0.31100.300.16 to 0.5680.650.33 to 1.30
Behavioural210.420.28 to 0.65190.310.20 to 0.4930.090.03 to 0.2800.00not estimated
General190.380.25 to 0.60220.360.24 to 0.55220.660.43 to 1.00201.631.05 to 2.52
(B) By time from diagnosis
Time from diagnosis6–12 months before3–6 months before1–3 months before0–1 month before
Symptom groupCountRate95% CICountRate95% CICountRate95% CICountRate95% CI
Headache161.651.01 to 2.6991.810.94 to 3.48226.464.25 to 9.814927.9621.13 to 36.99
Raised ICP10.100.01 to 0.7330.600.19 to 1.8730.880.28 to 2.731810.276.47 to 16.30
Convulsions60.620.28 to 1.37193.822.44 to 5.99102.931.58 to 5.4573.991.90 to 8.38
Visual disturbance90.930.48 to 1.7891.810.94 to 3.4882.351.17 to 4.69158.565.16 to 14.20
Focal deficits50.510.21 to 1.2420.400.10 to 1.6161.760.79 to 3.92147.994.73 to 13.49
Growth or endocrine70.720.34 to 1.5130.600.19 to 1.8720.590.15 to 2.3542.280.86 to 6.08
Behavioural40.410.15 to 1.1040.800.30 to 2.1410.290.04 to 2.0852.851.19 to 6.85
General50.510.21 to 1.2481.610.80 to 3.2292.641.37 to 5.082413.699.18 to 20.43
  • ICP, intracranial pressure,CPRD, Clinical Practice Research Datalink.