Table 2

Prescription drugs administered to boys with Duchenne muscular dystrophy (alphabetical order)

MedicineClassificationMode of actionIndicationDosage and routeApproximate cost/year
Bisoprolol fumarateβ-BlockerBlocks β-adrenoceptors in heartFirst signs of cardiomyopathy2.5–5 mg once daily; oral£15/$24 (based on 5 mg daily)
Deflazacort; used instead of prednisolone (prednisone)GlucocorticoidMultifunctional, immune modifyingUsual start from 4 to 6 years of age0.9 mg/kg once daily; oral£385/$616 (based on 24 mg daily)
OmeprazoleProton pump inhibitorReduces gastric acidPrevention of steroid-related ulcers10–20 mg once daily; oral£15/$24 (for both doses)
Perindopril erbumineAngiotensin-converting enzyme inhibitorInhibits conversion of angiotensin I into angiotensin IIFirst signs of cardiomyopathy2–4 mg once daily; oral£25/$40 (based on 4 mg daily)
Prednisolone (prednisone)GlucocorticoidMultifunctional, immune modifyingUsual start from 4 to 6 years of age0.75 mg/kg once daily; oral£68/$109 (based on 20 mg daily)
Risedronate sodiumBisphosphonateReduces rate of bone turnoverUsual start from 4 to 6 years of age35 mg once weekly; oral£ 14/$23 (for body weight >20 kg)
Vitamin D3VitaminHelps absorb calcium and phosphorusUsual start from 4 to 6 years of age800–1000 units daily; oral£ 44/$70 (based on 800 units daily)
  • Dosages must be cross-checked with local drug formulary; £1=$1.6.