Excipient | No. (%) of products (N=530)* | No. (%) of prescriptions (N=2095)* | No. (%) of neonates (N=726) |
---|---|---|---|
Solvents and solubilising agents | |||
Polysorbate 80 | 18 (3) | 139 (7) | 138 (19) |
Propylene glycol | 26 (5) | 129 (6) | 120 (17) |
Ethanol | 20 (4) | 47 (2) | 47 (7) |
Antimicrobials | |||
Parabens† | 71 (12) | 397 (19) | 313 (43) |
Benzoates‡ | 27 (5) | 93 (4) | 82 (11) |
Benzalkonium chloride | 10 (2) | 27 (1) | 26 (4) |
Sweeteners | |||
Saccharin sodium | 31 (6) | 104 (5) | 90 (12) |
Sorbitol | 24 (5) | 64 (3) | 57 (8) |
At least one excipients of interest | 142 (27) | 638 (31) | 456 (63) |
*Number of products and prescriptions with available excipient content data.
†Parabens include propylparabens, ethylparabens and methylparabens.
‡Benzoates include benzyl alcohol, benzoic acid and sodium benzoate.